[HTML][HTML] Genomic Evidence for the Evolution of Streptococcus equi: Host Restriction, Increased Virulence, and Genetic Exchange with Human Pathogens

MTG Holden, Z Heather, R Paillot, KF Steward… - PLoS …, 2009 - journals.plos.org
The continued evolution of bacterial pathogens has major implications for both human and
animal disease, but the exchange of genetic material between host-restricted pathogens is …

Genome specialization and decay of the strangles pathogen, Streptococcus equi, is driven by persistent infection

SR Harris, C Robinson, KF Steward, KS Webb… - Genome …, 2015 - genome.cshlp.org
Strangles, the most frequently diagnosed infectious disease of horses worldwide, is caused
by Streptococcus equi. Despite its prevalence, the global diversity and mechanisms …

[HTML][HTML] Combining two serological assays optimises sensitivity and specificity for the identification of Streptococcus equi subsp. equi exposure

C Robinson, KF Steward, N Potts, C Barker… - The veterinary …, 2013 - Elsevier
The detection of anti-Streptococcus equi antibodies in the blood serum of horses can assist
with the identification of apparently healthy persistently infected carriers and the prevention …

[HTML][HTML] Detection of Streptococcus equi subspecies equi using a triplex qPCR assay

…, C Barker, T Harrison, Z Heather, KF Steward… - The Veterinary …, 2013 - Elsevier
Genome sequencing data for Streptococcus equi subspecies equi and zooepidemicus were
used to develop a novel diagnostic triplex quantitative PCR (qPCR) assay targeting two …

A novel streptococcal integrative conjugative element involved in iron acquisition

Z Heather, MTG Holden, KF Steward… - Molecular …, 2008 - Wiley Online Library
In this study, we determined the function of a novel non‐ribosomal peptide synthetase (NRPS)
system carried by a streptococcal integrative conjugative element (ICE), ICESe2. The …

Identification of Three Novel Superantigen-Encoding Genes in Streptococcus equi subsp. zooepidemicus, szeF, szeN, and szeP

…, C Robinson, NL Wright, KF Steward… - Infection and …, 2010 - Am Soc Microbiol
The acquisition of superantigen-encoding genes by Streptococcus pyogenes has been
associated with increased morbidity and mortality in humans, and the gain of four superantigens …

[HTML][HTML] Metabolic implications of using BioOrthogonal Non-Canonical Amino Acid Tagging (BONCAT) for tracking protein synthesis

KF Steward, B Eilers, M Dorle, V Copié… - Frontiers in …, 2020 - frontiersin.org
BioOrthogonal Non-Canonical Amino acid Tagging (BONCAT) is a powerful tool for tracking
protein synthesis on the level of single cells within communities and whole organisms. A …

Globetrotting strangles: the unbridled national and international transmission of Streptococcus equi between horses

C Mitchell, KF Steward… - Microbial …, 2021 - microbiologyresearch.org
The equine disease strangles, which is characterized by the formation of abscesses in the
lymph nodes of the head and neck, is one of the most frequently diagnosed infectious …

Genomic dissection of an Icelandic epidemic of respiratory disease in horses and associated zoonotic cases

…, ÓG Sigurðardóttir, K Gammeljord, KF Steward… - MBio, 2017 - Am Soc Microbiol
Iceland is free of the major infectious diseases of horses. However, in 2010 an epidemic of
respiratory disease of unknown cause spread through the country’s native horse population …

Biodiesel: history of plant based oil usage and modern innovations

N Balasubramanian, KF Steward - Substantia, 2019 - torrossa.com
The history of biodiesel dates back to mid-19th century when transesterification of vegetable
oils was discovered. It took another half century for the world to realize its potential as fuel. …