The cyclic heptapeptide, microcystin-LR, inhibits protein phosphatases 1 (PP1) and 2A (PP2A)
with K i , values below 0.1 nM. Protein phosphatase 2B is inhibited 1000-fold less potently…

Cyanobacterial toxins have adverse effects on mammals, birds and fish and are being
increasingly recognised as a potent stress factor and health hazard factor in aquatic ecosystems. …

Recognition and repair of cellular damage is crucial if organisms are to survive harmful
environmental conditions. In mammals, the Keap1 protein orchestrates this response, but how it …

Dog deaths occurred in 1990 and 1991 after the animals drank water containing blooms of
benthic cyanobacteria along the shoreline of Loch Insh, Scotland. Signs of poisoning in the …

… Karen Beattie, for their knowledge and insight throughout this research project. In addition,
I am appreciative to Drs. Adachi and MacDermid for allowing me to attend their clinic to recruit …

During the last two decades, more than 100 cattle deaths have been reported from 11 alpine
sites in south-eastern Switzerland. Pathological findings and the histological examination of …

The effects of cyanotoxins on fish have been studied mainly in adults, rather than in early
life stages which could be more sensitive or, in view of their immobility, more readily affected. …

Colonies and single cells of Microcystis aeruginosa and the hepatotoxin microcystin were
retained by salad lettuce after growth with spray irrigation water containing the microcystin-…

Drug-induced Torsade-de-Pointes (TdP) has been responsible for the withdrawal of many
drugs from the market and is therefore of major concern to global regulatory agencies and the …

The commonly occurring cyanobacterial toxin microcystin‐LR (MC‐LR) was rapidly taken
up by the emergent reed plant Phragmites australis with clear distribution in the different …