Chronic obstructive pulmonary disease (COPD) is characterized by reduced lung function
and is the third leading cause of death globally. Through genome-wide association discovery …

Cannabis use is observationally associated with an increased risk of schizophrenia, but
whether the relationship is causal is not known. Using a genetic approach, we took 10 …

Importance Depression and obesity are 2 prevalent disorders that have been repeatedly
shown to be associated. However, the mechanisms and temporal sequence underlying this …

BACKGROUND: Major amputation is a dreaded event with high mortality and morbidity.
However, few studies have investigated the epidemiology of amputation in the elderly over time, …

Background Diabetic foot lesion is associated with increased morbidity and high resource
use. Although early amputation has been advocated in case of osteomyelitis, conservative …

Objectives To investigate the role of body mass index (BMI), systolic blood pressure, and
smoking behaviour in explaining the effect of education on the risk of cardiovascular disease …

Objective To determine whether educational attainment is a causal risk factor in the development
of coronary heart disease. Design Mendelian randomisation study, using genetic data …

The severe form of COVID-19 tends to be associated with neurological deficits. 1 2 Among
patients with acute respiratory distress syndrome (ARDS), who benefited from mechanical …

We introduce SSJ, an organized set of software tools implemented in the Java programming
language and offering general-purpose facilities for stochastic simulation programming. It …

Central Elysium Planitia (CEP) is located south of Elysium Mons. Back to the era of the
Viking orbiters, clues accumulated in favor of recent volcanism in relation with ground water …