The Zebrafish: A Powerful Platform for In Vivo, HTS Drug Discovery
C Delvecchio, J Tiefenbach… - Assay and drug …, 2011 - liebertpub.com
… 42 Makky KDuvnjak PPramanik KRamchandran RMayer ANA whole-animal microplate
assay for metabolic rate using zebrafishJ Biomol Screen200813960967. 42. Makky K, Duvnjak P…
assay for metabolic rate using zebrafishJ Biomol Screen200813960967. 42. Makky K, Duvnjak P…
[HTML][HTML] Estimating the global and regional burden of meningitis in children caused by Haemophilus influenzae type b: A systematic review and meta-analysis
Background Haemophilus influenzae Type B (Hib) meningitis caused significant public
health concern for children. Recent assessment in 2015 suggests vaccination has virtually …
health concern for children. Recent assessment in 2015 suggests vaccination has virtually …
[HTML][HTML] The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2
…, HP Ostendorff, M Golebiewski, J Tiefenbach… - The EMBO …, 2003 - embopress.org
Histone‐modifying enzymes play essential roles in physiological and aberrant gene
regulation. Since histone deacetylases (HDACs) are promising targets of cancer therapy, it is …
regulation. Since histone deacetylases (HDACs) are promising targets of cancer therapy, it is …
Role of the glymphatic system in idiopathic intracranial hypertension
This review discusses the potential significance of glymphatic system dysfunction in the
pathophysiology of idiopathic intracranial hypertension (IIH). IIH is a clinical syndrome …
pathophysiology of idiopathic intracranial hypertension (IIH). IIH is a clinical syndrome …
[HTML][HTML] The structural basis of gas-responsive transcription by the human nuclear hormone receptor REV-ERBβ
…, A Schuetz, A Dong, S Liu, R Zhang, J Tiefenbach… - PLoS …, 2009 - journals.plos.org
Heme is a ligand for the human nuclear receptors (NR) REV-ERBα and REV-ERBβ, which
are transcriptional repressors that play important roles in circadian rhythm, lipid and glucose …
are transcriptional repressors that play important roles in circadian rhythm, lipid and glucose …
[HTML][HTML] Multiple regions of ETO cooperate in transcriptional repression
D Hildebrand, J Tiefenbach, T Heinzel, M Grez… - Journal of Biological …, 2001 - ASBMB
In acute myeloid leukemias (AMLs) with t(8;21), the transcription factor AML1 is juxtaposed
to the zinc finger nuclear protein ETO (Eight-Twenty-One), resulting in transcriptional …
to the zinc finger nuclear protein ETO (Eight-Twenty-One), resulting in transcriptional …
Improving prediction of water quality indices using novel hybrid machine-learning algorithms
DT Bui, K Khosravi, J Tiefenbacher, H Nguyen… - Science of the Total …, 2020 - Elsevier
River water quality assessment is one of the most important tasks to enhance water resources
management plans. A water quality index (WQI) considers several water quality variables …
management plans. A water quality index (WQI) considers several water quality variables …
[HTML][HTML] Mapping the spatial and temporal variability of flood hazard affected by climate and land-use changes in the future
… The transition probability matrix is represented through ( 0 ≤ P i j < 1 a n d ∑ j = 1 m P i j =
1 a n d ( i . j = 1.2 . … m ) ) . (5) P i j = [ P 11 P 12 … P 1 m P 21 P 22 … P 2 m ⋮ ⋮ ⋮ ⋮ ⋮ ⋮ ⋮ …
1 a n d ( i . j = 1.2 . … m ) ) . (5) P i j = [ P 11 P 12 … P 1 m P 21 P 22 … P 2 m ⋮ ⋮ ⋮ ⋮ ⋮ ⋮ ⋮ …
[HTML][HTML] Urban flood modeling using deep-learning approaches in Seoul, South Korea
… The convolutional layer is defined as:(5) y i = f b j + ∑ i k ij ∗ x i where y j is the j th output
for the … variable designated x i , b j is a trainable bias, and f denotes the nonlinear function. …
for the … variable designated x i , b j is a trainable bias, and f denotes the nonlinear function. …
Improvement of best first decision trees using bagging and dagging ensembles for flood probability mapping
…, BT Pham, B Pradhan, JP Tiefenbacher - Water Resources …, 2020 - Springer
Abstract Development of zoning and flood-forecasting models is essential for making
optimal management decisions before and after floods. The Komijan watershed of Markazi …
optimal management decisions before and after floods. The Komijan watershed of Markazi …