Results of behavioral genetic and molecular genetic studies have converged to suggest that
both genetic and nongenetic factors contribute to the development of attention-deficit/…

Family, twin, and adoption studies have been essential in defining the genetic epidemiology
of bipolar disorder over the past several decades. Family studies have documented that first…

Genome-wide association studies have identified many variants that each affects multiple
traits, particularly across autoimmune diseases, cancers and neuropsychiatric disorders, …

For this edition, a number of typographical errors and minor slip-ups have been corrected.
In addition, following the persistent encouragement of Olga Oleinik, I have added a new …

Schizophrenia is a highly heritable disorder. Genetic risk is conferred by a large number of
alleles, including common alleles of small effect that might be detected by genome-wide …

Background Data for front-line health-care workers and risk of COVID-19 are limited. We
sought to assess risk of COVID-19 among front-line health-care workers compared with the …

Abstract Information processing in the cerebral cortex involves interactions among distributed
areas. Anatomical connectivity suggests that certain areas form local hierarchical relations …

To identify susceptibility loci for bipolar disorder, we tested 1.8 million variants in 4,387 cases
and 6,209 controls and identified a region of strong association (rs10994336, P = 9.1 × 10 −…

Rare coding variation has historically provided the most direct connections between gene
function and disease pathogenesis. By meta-analysing the whole exomes of 24,248 …

Population stratification refers to differences in allele frequencies between cases and controls
due to systematic differences in ancestry rather than association of genes with disease. It …