Biopolymer stereocomplexes
J Slager, AJ Domb - Advanced drug delivery reviews, 2003 - Elsevier
A polymer stereocomplex is defined as a stereoselective interaction between two
complementing stereoregular polymers, that interlock and form a new composite, demonstrating …
complementing stereoregular polymers, that interlock and form a new composite, demonstrating …
[HTML][HTML] Hard-wired control of bacterial processes by chromosomal gene location
J Slager, JW Veening - Trends in microbiology, 2016 - cell.com
Bacterial processes, such as stress responses and cell differentiation, are controlled at many
different levels. While some factors, such as transcriptional regulation, are well appreciated, …
different levels. While some factors, such as transcriptional regulation, are well appreciated, …
[HTML][HTML] iPSC-derived organ-on-a-chip models for personalized human genetics and pharmacogenomics studies
Genome-wide association studies (GWAS) have now correlated hundreds of genetic variants
with complex genetic diseases and drug efficacy. Functional characterization of these …
with complex genetic diseases and drug efficacy. Functional characterization of these …
[PDF][PDF] Antibiotic-induced replication stress triggers bacterial competence by increasing gene dosage near the origin
Streptococcus pneumoniae (pneumococcus) kills nearly 1 million children annually, and the
emergence of antibiotic-resistant strains poses a serious threat to human health. Because …
emergence of antibiotic-resistant strains poses a serious threat to human health. Because …
Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor
In order to establish the structural requirements for binding to the brain cannabinoid receptor
(CB 1 ), we have synthesized numerous fatty acid amides, ethanolamides, and some …
(CB 1 ), we have synthesized numerous fatty acid amides, ethanolamides, and some …
High‐throughput CRISPRi phenotyping identifies new essential genes in Streptococcus pneumoniae
…, C Gallay, M Kjos, A Domenech, J Slager… - Molecular systems …, 2017 - embopress.org
Genome‐wide screens have discovered a large set of essential genes in the opportunistic
human pathogen Streptococcus pneumoniae. However, the functions of many essential …
human pathogen Streptococcus pneumoniae. However, the functions of many essential …
National partnership for maternal safety: consensus bundle on severe hypertension during pregnancy and the postpartum period
Complications arising from hypertensive disorders of pregnancy are among the leading
causes of preventable severe maternal morbidity and mortality. Timely and appropriate …
causes of preventable severe maternal morbidity and mortality. Timely and appropriate …
[HTML][HTML] Time-resolved dual RNA-seq reveals extensive rewiring of lung epithelial and pneumococcal transcriptomes during early infection
R Aprianto, J Slager, S Holsappel, JW Veening - Genome biology, 2016 - Springer
Background Streptococcus pneumoniae, the pneumococcus, is the main etiological agent
of pneumonia. Pneumococcal infection is initiated by bacterial adherence to lung epithelial …
of pneumonia. Pneumococcal infection is initiated by bacterial adherence to lung epithelial …
Deep genome annotation of the opportunistic human pathogen Streptococcus pneumoniae D39
J Slager, R Aprianto, JW Veening - Nucleic acids research, 2018 - academic.oup.com
A precise understanding of the genomic organization into transcriptional units and their
regulation is essential for our comprehension of opportunistic human pathogens and how they …
regulation is essential for our comprehension of opportunistic human pathogens and how they …
Enterovirus D68 receptor requirements unveiled by haploid genetics
…, LT Jae, Y Liu, H Guo, JJ Slager… - Proceedings of the …, 2016 - National Acad Sciences
Enterovirus D68 (EV-D68) is an emerging pathogen that can cause severe respiratory
disease and is associated with cases of paralysis, especially among children. Heretofore, …
disease and is associated with cases of paralysis, especially among children. Heretofore, …