User profiles for J. Sidhaye

Jaydeep Sidhaye

IMBA, Vienna
Verified email at imba.oeaw.ac.at
Cited by 486

Brain organoids: an ensemble of bioassays to investigate human neurodevelopment and disease

J Sidhaye, JA Knoblich - Cell Death & Differentiation, 2021 - nature.com
Understanding etiology of human neurological and psychiatric diseases is challenging.
Genomic changes, protracted development, and histological features unique to human brain …

[PDF][PDF] Interkinetic nuclear migration is centrosome independent and ensures apical cell division to maintain tissue integrity

PJ Strzyz, HO Lee, J Sidhaye, IP Weber, LC Leung… - Developmental cell, 2015 - cell.com
Pseudostratified epithelia are widespread during animal development and feature elongated
cells whose nuclei adopt various positions along the apicobasal cell axis. Before mitosis, …

Concerted action of neuroepithelial basal shrinkage and active epithelial migration ensures efficient optic cup morphogenesis

J Sidhaye, C Norden - elife, 2017 - elifesciences.org
… Copyright Sidhaye and Norden. This article is distributed under the terms of the Creative
Commons Attribution License, which permits unrestricted use and redistribution provided that …

Integrated transcriptome and proteome analysis reveals posttranscriptional regulation of ribosomal genes in human brain organoids

J Sidhaye, P Trepte, N Sepke, M Novatchkova… - Elife, 2023 - elifesciences.org
During development of the human cerebral cortex, multipotent neural progenitors generate
excitatory neurons and glial cells. Investigations of the transcriptome and epigenome have …

[PDF][PDF] Collective cell migration during optic cup formation features changing cell-matrix interactions linked to matrix topology

KG Soans, AP Ramos, J Sidhaye, A Krishna… - Current Biology, 2022 - cell.com
… to fluorescent proteins BAC recombineering was performed in the transgenomics facility at
MPI-CBG using a previously published protocol57 (Protocol description adapted from Sidhaye

Using light sheet fluorescence microscopy to image zebrafish eye development

J Icha, C Schmied, J Sidhaye, P Tomancak… - JoVE (Journal of …, 2016 - jove.com
… (I) xy section and (J) yz section of the same data after multiview deconvolution, showing a
significant increase in resolution and contrast of the signal both in xy and in z. Images in (EJ) …

Morphogenesis and development of human telencephalic organoids in the absence and presence of exogenous extracellular matrix

C Martins‐Costa, VA Pham, J Sidhaye… - The EMBO …, 2023 - embopress.org
J. Experimental paradigm to test the effect of liquid embedding with purified Laminin or
Collagen … J, K. Quantification of the ratio of telencephalic/non-telencephalic (FOGX1 + /OTX2 + ) (…

[HTML][HTML] The zebrafish goosepimples/myosin Vb mutant exhibits cellular attributes of human microvillus inclusion disease

J Sidhaye, CS Pinto, S Dharap, T Jacob… - Mechanisms of …, 2016 - Elsevier
… Arrows in B–E and J point to the intestinal folds. The square brackets show the comparison
and asterisks indicate the statistically significant difference at p < 0.05 by Student's t-test. The …

[HTML][HTML] Myosin Vb mediated plasma membrane homeostasis regulates peridermal cell size and maintains tissue homeostasis in the zebrafish epidermis

Sonal, J Sidhaye, M Phatak, S Banerjee, A Mulay… - PLoS …, 2014 - journals.plos.org
… Scale bars in E and J correspond to 20 µ in B–E and G–J, respectively. … Arrows in H and J
point to the rounded up peridermal cells over larval head, which is a classic feature of myosin …

Morphogenesis and development of human telencephalic organoids in the absence and presence of exogenous ECM

C Martins-Costa, V Pham, J Sidhaye, M Novatchkova… - BioRxiv, 2022 - biorxiv.org
Establishment and maintenance of apical-basal polarity is a fundamental step in brain
development, instructing the organization of neural progenitor cells (NPCs) and the developing …