Lead neurotoxicity in children: basic mechanisms and clinical correlates
TI Lidsky, JS Schneider - Brain, 2003 - academic.oup.com
Lead has been recognized as a poison for millennia and has been the focus of public health
regulation in much of the developed world for the better part of the past century. The nature …
regulation in much of the developed world for the better part of the past century. The nature …
Manganese: recent advances in understanding its transport and neurotoxicity
The present review is based on presentations from the meeting of the Society of Toxicology
in San Diego, CA (March 2006). It addresses recent developments in the understanding of …
in San Diego, CA (March 2006). It addresses recent developments in the understanding of …
Sensory and cognitive functions of the basal ganglia
LL Brown, JS Schneider, TI Lidsky - Current opinion in neurobiology, 1997 - Elsevier
Recent studies have found that the basal ganglia are involved in diverse behavioral activities
and suggest that they have executive functions. Highlights from the past year include …
and suggest that they have executive functions. Highlights from the past year include …
[HTML][HTML] Cell-free formation of RNA granules: low complexity sequence domains form dynamic fibers within hydrogels
Eukaryotic cells contain assemblies of RNAs and proteins termed RNA granules. Many proteins
within these bodies contain KH or RRM RNA-binding domains as well as low complexity …
within these bodies contain KH or RRM RNA-binding domains as well as low complexity …
[PDF][PDF] The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche
Bone marrow transplantation is the primary therapy for numerous hematopoietic disorders.
The efficiency of bone marrow transplantation depends on the function of long-term …
The efficiency of bone marrow transplantation depends on the function of long-term …
Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation
W Gu, JW Schneider, G Condorelli, S Kaushal… - Cell, 1993 - cell.com
The experiments reported here document that the tumor suppressor retinoblastoma protein (pRB)
plays an important role in the production and maintenance of the terminally …
plays an important role in the production and maintenance of the terminally …
The neurobiological basis of cognitive impairment in Parkinson's disease
The recent formalization of clinical criteria for Parkinson's disease with dementia (PDD)
codifies many studies on this topic, including those assessing biological correlates. These …
codifies many studies on this topic, including those assessing biological correlates. These …
Doxorubicin blocks cardiomyocyte autophagic flux by inhibiting lysosome acidification
Background— The clinical use of doxorubicin is limited by cardiotoxicity. Histopathological
changes include interstitial myocardial fibrosis and the appearance of vacuolated …
changes include interstitial myocardial fibrosis and the appearance of vacuolated …
Reversal of Terminal Differentiation Mediated by p107 in Rb-/- Muscle Cells
JW Schneider, W Gu, L Zhu, V Mahdavi… - Science, 1994 - science.org
The terminal differentiation of mammalian muscle cells requires the tumor suppressor
retinoblastoma protein (Rb). Unlike their wild-type counterparts, multinucleated myotubes from …
retinoblastoma protein (Rb). Unlike their wild-type counterparts, multinucleated myotubes from …
Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing
…, WH Zimmermann, R Bassel-Duby, JW Schneider… - Science …, 2018 - science.org
Genome editing with CRISPR/Cas9 is a promising new approach for correcting or mitigating
disease-causing mutations. Duchenne muscular dystrophy (DMD) is associated with lethal …
disease-causing mutations. Duchenne muscular dystrophy (DMD) is associated with lethal …