We gathered genomic data from grapes (Vitis vinifera ssp. vinifera), a clonally propagated
perennial crop, to address three ongoing mysteries about plant domestication. The first is the …

Land tenure security is increasingly recognized as a foundational element for advancing global
sustainable development agendas, but questions remain about how it affects human well…

Modern molecular genetic datasets, primarily collected to study the biology of human health
and disease, can be used to directly measure the action of natural selection and reveal …

While evidence exists supporting the potential for aerosol transmission of SARS-CoV-2, the
infectious dose by inhalation remains unknown. In the present study, the probability of …

Background Radiation therapy is integral to effective thoracic cancer treatments, but its
application is limited by sensitivity of critical organs such as the heart. The impacts of acute …

Background The United Nations recently made a call to address the challenges of an estimated
300 million persons worldwide living with a rare disease through the collection, analysis, …

… For a diploid with m i causative mutations on the i th haplotype, we may define the additive
model as (1) where c i,j is the effect size of the j th mutation on the i th haplotype. Each c i,j is …

Gottingen minipigs mirror the physiological radiation response observed in humans and
hence make an ideal candidate model for studying radiation biodosimetry for both limited-sized …

Objective Identifying sets of rare diseases with shared aspects of etiology and pathophysiology
may enable drug repurposing. Toward that aim, we utilized an integrative knowledge …

Background Glioblastoma (GBM) is the most aggressive and common malignant primary
brain tumor; however, treatment remains a significant challenge. This study aims to identify …