User profiles for J. Quackenbush

John Quackenbush

Harvard TH Chan School of Public Health, Channing Division of Network Medicine, and …
Verified email at hsph.harvard.edu
Cited by 96006

[9] TM4 microarray software suite

…, J Li, M Thiagarajan, JA White, J Quackenbush - Methods in …, 2006 - Elsevier
Powerful specialized software is essential for managing, quantifying, and ultimately deriving
scientific insight from results of a microarray experiment. We have developed a suite of …

Artificial intelligence in radiology

A Hosny, C Parmar, J Quackenbush… - Nature Reviews …, 2018 - nature.com
Artificial intelligence (AI) algorithms, particularly deep learning, have demonstrated
remarkable progress in image-recognition tasks. Methods ranging from convolutional neural …

Microarray data normalization and transformation

J Quackenbush - Nature genetics, 2002 - nature.com
Underlying every microarray experiment is an experimental question that one would like to
address. Finding a useful and satisfactory answer relies on careful experimental design and …

Minimum information about a microarray experiment (MIAME)—toward standards for microarray data

A Brazma, P Hingamp, J Quackenbush, G Sherlock… - Nature …, 2001 - nature.com
Microarray analysis has become a widely used tool for the generation of gene expression data
on a genomic scale. Although many significant results have been derived from microarray …

[HTML][HTML] The complete genome sequence of the gastric pathogen Helicobacter pylori

…, S Gill, BA Dougherty, K Nelson, J Quackenbush… - Nature, 1997 - nature.com
Helicobacter pylori, strain 26695, has a circular genome of 1,667,867 base pairs and 1,590
predicted coding sequences. Sequence analysis indicates that H. pylori has well-developed …

TM4: a free, open-source system for microarray data management and analysis

…, Z Liu, A Vinsavich, V Trush, J Quackenbush - …, 2003 - Future Science
BioTechniques 34: 374-378 (February 2003) supported, MADAM is being adapted to read
and write MAGE-ML, the XML data exchange format being developed by an international …

[HTML][HTML] Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach

…, CR Leemans, A Dekker, J Quackenbush… - Nature …, 2014 - nature.com
Human cancers exhibit strong phenotypic differences that can be visualized noninvasively
by medical imaging. Radiomics refers to the comprehensive quantification of tumour …

[HTML][HTML] Supervised risk predictor of breast cancer based on intrinsic subtypes

…, JF Quackenbush, IJ Stijleman, J Palazzo… - Journal of clinical …, 2009 - ncbi.nlm.nih.gov
Purpose To improve on current standards for breast cancer prognosis and prediction of
chemotherapy benefit by developing a risk model that incorporates the gene expression–based “…

[HTML][HTML] Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi

…, J Peterson, AR Kerlavage, J Quackenbush… - Nature, 1997 - nature.com
The genome of the bacterium Borrelia burgdorferi B31, the aetiologic agent of Lyme disease,
contains a linear chromosome of 910,725 base pairs and at least 17 linear and circular …

TIGR Gene Indices clustering tools (TGICL): a software system for fast clustering of large EST datasets

…, F Cheung, B Parvizi, J Tsai, J Quackenbush - …, 2003 - academic.oup.com
TGICL is a pipeline for analysis of large Expressed Sequence Tags (EST) and mRNA databases
in which the sequences are first clustered based on pairwise sequence similarity, and …