[HTML][HTML] Extracellular vesicles secreted by Schistosoma mansoni contain protein vaccine candidates

J Sotillo, M Pearson, J Potriquet, L Becker… - International journal for …, 2016 - Elsevier
Herein we show for the first time that Schistosoma mansoni adult worms secrete exosome-like
extracellular vesicles ranging from 50 to 130 nm in size. Extracellular vesicles were …

Carcinogenic liver fluke secretes extracellular vesicles that promote cholangiocytes to adopt a tumorigenic phenotype

…, J Potriquet, M Laohaviroj, J Mulvenna… - The Journal of …, 2015 - academic.oup.com
Background. Throughout Asia, there is an unprecedented link between cholangiocarcinoma
and infection with the liver fluke Opisthorchis viverrini. Multiple processes, including chronic …

[HTML][HTML] Transcriptome and venom proteome of the box jellyfish Chironex fleckeri

…, J Potriquet, D Kumar, D Dash, D Kvaskoff, J Mulvenna - BMC genomics, 2015 - Springer
Background The box jellyfish, Chironex fleckeri, is the largest and most dangerous cubozoan
jellyfish to humans. It produces potent and rapid-acting venom and its sting causes severe …

[HTML][HTML] Tentacle Transcriptome and Venom Proteome of the Pacific Sea Nettle, Chrysaora fuscescens (Cnidaria: Scyphozoa)

D Ponce, DL Brinkman, J Potriquet, J Mulvenna - Toxins, 2016 - mdpi.com
Jellyfish venoms are rich sources of toxins designed to capture prey or deter predators, but
they can also elicit harmful effects in humans. In this study, an integrated transcriptomic and …

[HTML][HTML] A modified FASP protocol for high-throughput preparation of protein samples for mass spectrometry

J Potriquet, M Laohaviroj, JM Bethony, J Mulvenna - PloS one, 2017 - journals.plos.org
To facilitate high-throughput proteomic analyses we have developed a modified FASP
protocol which improves the rate at which protein samples can be processed prior to mass …

[HTML][HTML] Venom Proteome of the Box Jellyfish Chironex fleckeri

…, A Aziz, A Loukas, J Potriquet, J Seymour, J Mulvenna - PloS one, 2012 - journals.plos.org
The nematocyst is a complex intracellular structure unique to Cnidaria. When triggered to
discharge, the nematocyst explosively releases a long spiny, tubule that delivers an often …

[HTML][HTML] Qualitative and quantitative proteomic analyses of Schistosoma japonicum eggs and egg-derived secretory-excretory proteins

…, J Potriquet, H You, DP McManus, J Mulvenna… - Parasites & vectors, 2019 - Springer
Background Schistosome parasites lay up to a thousand eggs per day inside the veins of
their mammalian hosts. The immature eggs deposited by females against endothelia of …

Unique molecular profile of exosomes derived from primary human proximal tubular epithelial cells under diseased conditions

…, K Kildey, J Potriquet, J Mulvenna… - Journal of …, 2017 - Taylor & Francis
Human proximal tubular epithelial cells (PTEC) of the kidney are known to respond to and
mediate the disease process in a wide range of kidney diseases, yet their exosomal …

[HTML][HTML] A microRNA profile associated with Opisthorchis viverrini-induced cholangiocarcinoma in tissue and plasma

…, G Rinaldi, Y Feng, J Peng, S Easley, X Jia, J Potriquet… - BMC cancer, 2015 - Springer
Background Intrahepatic cholangiocarcinoma (ICC) is a highly aggressive tumor of the bile
duct, and a significant public health problem in East Asia, where it is associated with infection …

[HTML][HTML] Kunitz type protease inhibitor EgKI-1 from the canine tapeworm Echinococcus granulosus as a promising therapeutic against breast cancer

SL Ranasinghe, GM Boyle, K Fischer, J Potriquet… - PloS one, 2018 - journals.plos.org
EgKI-1, a member of the Kunitz type protease inhibitor family, is highly expressed by the
oncosphere of the canine tapeworm Echinococcus granulosus, the stage that is infectious to …