Toward a new history and geography of human genes informed by ancient DNA
JK Pickrell, D Reich - Trends in Genetics, 2014 - cell.com
Genetic information contains a record of the history of our species, and technological advances
have transformed our ability to access this record. Many studies have used genome-wide …
have transformed our ability to access this record. Many studies have used genome-wide …
The complete genome sequence of a Neanderthal from the Altai Mountains
…, C Theunert, A Tandon, P Moorjani, J Pickrell… - Nature, 2014 - nature.com
We present a high-quality genome sequence of a Neanderthal woman from Siberia. We
show that her parents were related at the level of half-siblings and that mating among close …
show that her parents were related at the level of half-siblings and that mating among close …
Inference of population splits and mixtures from genome-wide allele frequency data
J Pickrell, J Pritchard - Nature Precedings, 2012 - nature.com
… We divided the residual distance between each pair of populations i and j by the average
standard error across all pairs. We then plot in each cell [i, j] this scaled residual. Colors are …
standard error across all pairs. We then plot in each cell [i, j] this scaled residual. Colors are …
Genome-wide patterns of selection in 230 ancient Eurasians
Ancient DNA makes it possible to observe natural selection directly by analysing samples
from populations before, during and after adaptation events. Here we report a genome-wide …
from populations before, during and after adaptation events. Here we report a genome-wide …
The formation of false memories
EF Loftus, JE Pickrell - Psychiatric annals, 1995 - journals.healio.com
by ELIZABETH F. LOFTUS, PhD; and JACQUELINE E. PICKRELL, BA or most of this century,
experimental psychologists have been interested in how and why memory fails. As Greene…
experimental psychologists have been interested in how and why memory fails. As Greene…
Understanding mechanisms underlying human gene expression variation with RNA sequencing
… The project was designed and supervised by YG and JK Pritchard with regular input from
MS The paper was written by JK Pickrell, YG and JK Pritchard, with input from all authors. …
MS The paper was written by JK Pickrell, YG and JK Pritchard, with input from all authors. …
Genome-wide association study identifies 74 loci associated with educational attainment
Educational attainment is strongly influenced by social and other environmental factors, but
genetic factors are estimated to account for at least 20% of the variation across individuals 1. …
genetic factors are estimated to account for at least 20% of the variation across individuals 1. …
New approaches for the evaluation of pulmonary toxicity: bronchoalveolar lavage fluid analysis
…, JL Mauderly, RO McClellan, JA Pickrell - … and Applied Toxicology, 1985 - Elsevier
Abstract Analysis of bronchoalveolar lavage fluid (BAL) is an effective method of detecting
an inflammatory response in the lungs of animals in toxicological studies. Alterations in BAL …
an inflammatory response in the lungs of animals in toxicological studies. Alterations in BAL …
A systematic survey of loss-of-function variants in human protein-coding genes
Genome-sequencing studies indicate that all humans carry many genetic variants predicted
to cause loss of function (LoF) of protein-coding genes, suggesting unexpected redundancy …
to cause loss of function (LoF) of protein-coding genes, suggesting unexpected redundancy …
Detection and interpretation of shared genetic influences on 42 human traits
… [i,j], we extracted the set of variants that influence trait i and their effect sizes on both i and j.
… effect sizes on i and the effect sizes on j and tested whether this correlation was significantly …
… effect sizes on i and the effect sizes on j and tested whether this correlation was significantly …