Physiological changes in respiratory function associated with ageing
JP Janssens, JC Pache… - European Respiratory …, 1999 - Eur Respiratory Soc
Physiological ageing of the lung is associated with dilatation of alveoli, enlargement of
airspaces, decrease in exchange surface area and loss of supporting tissue for peripheral …
airspaces, decrease in exchange surface area and loss of supporting tissue for peripheral …
[HTML][HTML] Analysis of 14 trials comparing sirolimus-eluting stents with bare-metal stents
A Kastrati, J Mehilli, J Pache, C Kaiser… - … England Journal of …, 2007 - Mass Medical Soc
Background The long-term effects of treatment with sirolimus-eluting stents, as compared
with bare-metal stents, have not been established. Methods We performed an analysis of …
with bare-metal stents, have not been established. Methods We performed an analysis of …
Abciximab in patients with acute coronary syndromes undergoing percutaneous coronary intervention after clopidogrel pretreatment: the ISAR-REACT 2 randomized …
…, J Ten Berg, H Bollwein, I Graf, M Ibrahim, J Pache… - Jama, 2006 - jamanetwork.com
ContextNo specifically designed studies have addressed the role of the glycoprotein IIb/IIIa
inhibitor abciximab in patients with non–ST-segment elevation acute coronary syndromes (…
inhibitor abciximab in patients with non–ST-segment elevation acute coronary syndromes (…
Sirolimus-eluting stent or paclitaxel-eluting stent vs balloon angioplasty for prevention of recurrences in patients with coronary in-stent restenosis: a randomized …
…, N Von Beckerath, A Dibra, J Hausleiter, J Pache… - Jama, 2005 - jamanetwork.com
ContextIn patients with de novo coronary lesions, drug-eluting stents have drastically reduced
restenosis risk compared with bare metal stents and conventional balloon angioplasty. It is …
restenosis risk compared with bare metal stents and conventional balloon angioplasty. It is …
Intracoronary stenting and angiographic results: strut thickness effect on restenosis outcome (ISAR-STEREO-2) trial
JÜ Pache, A Kastrati, J Mehilli, H Schühlen… - Journal of the American …, 2003 - jacc.org
Objectives : We tested the hypothesis that thinner-strut stents are associated with a reduced
rate of restenosis when comparing two stents with different design. Background : We have …
rate of restenosis when comparing two stents with different design. Background : We have …
Diabetes mellitus and the clinical and angiographic outcome after coronary stent placement
S Elezi, A Kastrati, J Pache, A Wehinger… - Journal of the American …, 1998 - jacc.org
Objectives. The objectives of this study were to analyze the clinical and angiographic
outcome of diabetic patients with successful coronary stent placement and to compare these …
outcome of diabetic patients with successful coronary stent placement and to compare these …
[HTML][HTML] Paclitaxel-eluting or sirolimus-eluting stents to prevent restenosis in diabetic patients
A Dibra, A Kastrati, J Mehilli, J Pache… - … England Journal of …, 2005 - Mass Medical Soc
Background Drug-eluting stents are highly effective in reducing the rate of in-stent restenosis.
It is not known whether there are differences in the effectiveness of currently approved drug…
It is not known whether there are differences in the effectiveness of currently approved drug…
5-year prognostic value of no-reflow phenomenon after percutaneous coronary intervention in patients with acute myocardial infarction
…, RA Byrne, J Pache, P Alger, J Mehilli… - Journal of the American …, 2010 - jacc.org
Objectives : The objective of this study was to investigate the impact of no-reflow phenomenon
on 5-year mortality among patients with acute ST-segment elevation myocardial infarction …
on 5-year mortality among patients with acute ST-segment elevation myocardial infarction …
[HTML][HTML] Coronary stenting plus platelet glycoprotein IIb/IIIa blockade compared with tissue plasminogen activator in acute myocardial infarction
…, J Mehilli, U Schricke, J Pache… - … England Journal of …, 2000 - Mass Medical Soc
Background Prevention of myocardial damage is the main goal of all reperfusion therapies
in patients with acute myocardial infarction. The relative efficacy of various reperfusion …
in patients with acute myocardial infarction. The relative efficacy of various reperfusion …
[HTML][HTML] DDR1 role in fibrosis and its pharmacological targeting
S Moll, A Desmoulière, MJ Moeller, JC Pache… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Discoidin domain receptor1 (DDR1) is a collagen activated receptor tyrosine kinase and an
attractive anti-fibrotic target. Its expression is mainly limited to epithelial cells located in …
attractive anti-fibrotic target. Its expression is mainly limited to epithelial cells located in …