Physiological changes in respiratory function associated with ageing

JP Janssens, JC Pache… - European Respiratory …, 1999 - Eur Respiratory Soc
Physiological ageing of the lung is associated with dilatation of alveoli, enlargement of
airspaces, decrease in exchange surface area and loss of supporting tissue for peripheral …

[HTML][HTML] Analysis of 14 trials comparing sirolimus-eluting stents with bare-metal stents

A Kastrati, J Mehilli, J Pache, C Kaiser… - … England Journal of …, 2007 - Mass Medical Soc
Background The long-term effects of treatment with sirolimus-eluting stents, as compared
with bare-metal stents, have not been established. Methods We performed an analysis of …

Abciximab in patients with acute coronary syndromes undergoing percutaneous coronary intervention after clopidogrel pretreatment: the ISAR-REACT 2 randomized …

…, J Ten Berg, H Bollwein, I Graf, M Ibrahim, J Pache… - Jama, 2006 - jamanetwork.com
ContextNo specifically designed studies have addressed the role of the glycoprotein IIb/IIIa
inhibitor abciximab in patients with non–ST-segment elevation acute coronary syndromes (…

Sirolimus-eluting stent or paclitaxel-eluting stent vs balloon angioplasty for prevention of recurrences in patients with coronary in-stent restenosis: a randomized …

…, N Von Beckerath, A Dibra, J Hausleiter, J Pache… - Jama, 2005 - jamanetwork.com
ContextIn patients with de novo coronary lesions, drug-eluting stents have drastically reduced
restenosis risk compared with bare metal stents and conventional balloon angioplasty. It is …

Intracoronary stenting and angiographic results: strut thickness effect on restenosis outcome (ISAR-STEREO-2) trial

Pache, A Kastrati, J Mehilli, H Schühlen… - Journal of the American …, 2003 - jacc.org
Objectives : We tested the hypothesis that thinner-strut stents are associated with a reduced
rate of restenosis when comparing two stents with different design. Background : We have …

Diabetes mellitus and the clinical and angiographic outcome after coronary stent placement

S Elezi, A Kastrati, J Pache, A Wehinger… - Journal of the American …, 1998 - jacc.org
Objectives. The objectives of this study were to analyze the clinical and angiographic
outcome of diabetic patients with successful coronary stent placement and to compare these …

[HTML][HTML] Paclitaxel-eluting or sirolimus-eluting stents to prevent restenosis in diabetic patients

A Dibra, A Kastrati, J Mehilli, J Pache… - … England Journal of …, 2005 - Mass Medical Soc
Background Drug-eluting stents are highly effective in reducing the rate of in-stent restenosis.
It is not known whether there are differences in the effectiveness of currently approved drug…

5-year prognostic value of no-reflow phenomenon after percutaneous coronary intervention in patients with acute myocardial infarction

…, RA Byrne, J Pache, P Alger, J Mehilli… - Journal of the American …, 2010 - jacc.org
Objectives : The objective of this study was to investigate the impact of no-reflow phenomenon
on 5-year mortality among patients with acute ST-segment elevation myocardial infarction …

[HTML][HTML] Coronary stenting plus platelet glycoprotein IIb/IIIa blockade compared with tissue plasminogen activator in acute myocardial infarction

…, J Mehilli, U Schricke, J Pache… - … England Journal of …, 2000 - Mass Medical Soc
Background Prevention of myocardial damage is the main goal of all reperfusion therapies
in patients with acute myocardial infarction. The relative efficacy of various reperfusion …

[HTML][HTML] DDR1 role in fibrosis and its pharmacological targeting

S Moll, A Desmoulière, MJ Moeller, JC Pache… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Discoidin domain receptor1 (DDR1) is a collagen activated receptor tyrosine kinase and an
attractive anti-fibrotic target. Its expression is mainly limited to epithelial cells located in …