The natural killer (NK)-cell immunological synapse is the dynamic interface formed between
an NK cell and its target cell. Formation of the NK-cell immunological synapse involves …

Human immunoglobulin prepared for intravenous administration (IGIV) has a number of
important uses in the treatment of disease. Some of these are in diseases for which acceptable …

… The CD56 bright and CD56 dim subpopulations of NK cells are encircled by the orange
and red gates, respectively. Perforin content within these populations is depicted in the …

Two seemingly unrelated hallmarks of memory CD8 + T cells are cytokine-driven
proliferative renewal after pathogen clearance and a latent effector program in anticipation of …

Introduction Wiskott-Aldrich syndrome (WAS) is a primary immunodeficiency characterized
by eczema, thrombocytopenia, infections, and a high risk of developing autoimmunity and …

Natural killer cells constitute 50–90% of lymphocytes in human uterine decidua in early
pregnancy. Here, CD56 bright uterine decidual NK (dNK) cells were compared with the CD56 …

A hallmark of mammalian immunity is the heterogeneity of cell fate that exists among
pathogen-experienced lymphocytes. We show that a dividing T lymphocyte initially responding to a …

The American Academy of Allergy, Asthma & Immunology (AAAAI) and the American
College of Allergy, Asthma & Immunology (ACAAI) have jointly accepted responsibility for …

Importance Newborn screening for severe combined immunodeficiency (SCID) using assays
to detect T-cell receptor excision circles (TRECs) began in Wisconsin in 2008, and SCID …

The purpose of this Practice Parameter for the Diagnosis and Management of Primary
Immunodeficiency is to provide the consultant allergist/immunologist with a practical guide for the …