A protein phosphatase network controls the temporal and spatial dynamics of differentiation commitment in human epidermis

…, G Walko, P Viswanathan, M Tihy, J Nijjher… - Elife, 2017 - elifesciences.org
… (j) Histogram of normalised SILAC ratios corresponding to high confidence phosphorylation
sites that differ between 0 and 4 hr. (k) Scatter plot correlating log2 normalised SILAC ratios …

[HTML][HTML] MiR-155 has a protective role in the development of non-alcoholic hepatosteatosis in mice

AM Miller, DS Gilchrist, J Nijjar, E Araldi, CM Ramirez… - PloS one, 2013 - journals.plos.org
Hepatic steatosis is a global epidemic that is thought to contribute to the pathogenesis of
type 2 diabetes. MicroRNAs (miRs) are regulators that can functionally integrate a range of …

[HTML][HTML] The mannose receptor (CD206) identifies a population of colonic macrophages in health and inflammatory bowel disease

…, SL Clay, EV Robertson, F Morton, JS Nijjar… - Scientific reports, 2021 - nature.com
To understand the contribution of mononuclear phagocytes (MNP), which include monocyte-derived
intestinal macrophages, to the pathogenesis of inflammatory bowel disease (IBD), it …

Estimating optimal dynamic treatment regimes with survival outcomes

G Simoneau, EEM Moodie, JS Nijjar… - Journal of the …, 2020 - Taylor & Francis
… survival times T = ∑ j = 1 J η j T j . We define the counterfactual survival time T a = ∑ j = 1
J η j T j a j where T j a j denotes the potential survival time within stage j if, possibly contrary to …

The racialized surveillant assemblage: Islam and the fear of terrorism

S Sharma, J Nijjar - Popular Communication, 2018 - Taylor & Francis
Increasingly intense, multifaceted, and integrated forms of surveillance are a central feature
of Western national security attempts to counter the violence of “Islamic terrorism.” However, …

Inhibition of spleen tyrosine kinase in the treatment of rheumatoid arthritis

JS Nijjar, A Tindell, IB McInnes, S Siebert - Rheumatology, 2013 - academic.oup.com
The pathogenesis of RA is a complex and ever-changing landscape but amid the chaos of
the disease process we have found effective treatment regimes. However, our current …

[HTML][HTML] Postoperative pain after single-site versus multiport hysterectomy

C Kliethermes, K Blazek, K Ali, JB Nijjar… - JSLS: Journal of the …, 2017 - ncbi.nlm.nih.gov
Methods: Seventy patients were selected for this prospective cohort study, with 35 undergoing
multiple-incision and 35 undergoing LESS hysterectomy. All patients were included who …

The liver X receptor pathway is highly upregulated in rheumatoid arthritis synovial macrophages and potentiates TLR-driven cytokine release

DL Asquith, LE Ballantine, JS Nijjar… - Annals of the …, 2013 - ard.bmj.com
Objectives Macrophages are central to the inflammatory processes driving rheumatoid arthritis
(RA) synovitis. The molecular pathways that are induced in synovial macrophages and …

[HTML][HTML] Differential CpG DNA methylation in peripheral naïve CD4+ T-cells in early rheumatoid arthritis patients

…, R Parmar, K Mydlova, X Xie, A Droop, JS Nijjar… - Clinical …, 2020 - Springer
Background The genetic risk associated with rheumatoid arthritis (RA) includes genes regulating
DNA methylation, one of the hallmarks of epigenetic re-programing, as well as many T-…

Police–school partnerships and the war on black youth

JS Nijjar - Critical Social Policy, 2021 - journals.sagepub.com
This article discusses the growing presence of police officers in British schools, under a
resurgent police–school partnerships policy agenda in the ‘war on gangs’ and serious youth …