To flourish, cancers greatly depend on their surrounding tumor microenvironment (TME),
and cancer-associated fibroblasts (CAFs) in TME are critical for cancer occurrence and …

… junsheng Mu received his MS degree from Nanchang Hangkong University, China, in
2015, and his Ph.D. degree from Beijing University of Posts and Telecommunications in 2019. …

Background: Pollution–unwanted waste released to air, water, and land by human activity–is
the largest environmental cause of disease in the world today. It is responsible for an …

Glucose homeostasis depends on insulin responsiveness in target tissues, most importantly,
muscle and liver. The critical initial steps in insulin action include phosphorylation of …

Obesity is an epidemic in Western society, and causes rapidly accelerating rates of type 2
diabetes and cardiovascular disease. The evolutionarily conserved serine/threonine kinase, …

Replicative cell division is an energetically demanding process that can be executed only if
cells have sufficient metabolic resources to support a doubling of cell mass. Here we show …

Mitochondrial biogenesis is a critical adaptation to chronic energy deprivation, yet the signaling
mechanisms responsible for this response are poorly understood. To examine the role of …

… (J) Electron microscopy showing numerous coronavirus particles (arrow) in cytoplasm of …
2J). The majority of viral particles were intact, but a few fragmented virions were also visible. …

Eukaryotic cells possess systems for sensing nutritional stress and inducing compensatory
mechanisms that minimize the consumption of ATP while utilizing alternative energy sources. …

Widespread use of antimalarial agents can profoundly influence the evolution of the human
malaria parasite Plasmodium falciparum. Recent selective sweeps for drug-resistant …