User profiles for J. Marko
John F. MarkoProfessor, Molecular Biosciences and Physics & Astronomy, Northwestern University Verified email at northwestern.edu Cited by 23117 |
How do site‐specific DNA‐binding proteins find their targets?
SE Halford, JF Marko - Nucleic acids research, 2004 - academic.oup.com
Essentially all the biological functions of DNA depend on site‐specific DNA‐binding proteins
finding their targets, and therefore ‘searching’ through megabases of non‐target DNA. In …
finding their targets, and therefore ‘searching’ through megabases of non‐target DNA. In …
Chromatin's physical properties shape the nucleus and its functions
The cell nucleus encloses, organizes, and protects the genome. Chromatin maintains
nuclear mechanical stability and shape in coordination with lamins and the cytoskeleton. …
nuclear mechanical stability and shape in coordination with lamins and the cytoskeleton. …
From the radiologic pathology archives: Adrenal tumors and tumor-like conditions in the adult: radiologic-pathologic correlation
GE Lattin Jr, ED Sturgill, CA Tujo, J Marko… - Radiographics, 2014 - pubs.rsna.org
Advanced imaging often reveals adrenal tumors and tumor-like conditions in both symptomatic
and asymptomatic patients. When adrenal disease is clinically suspected, cross-sectional …
and asymptomatic patients. When adrenal disease is clinically suspected, cross-sectional …
Stretching dna
A statistical mechanical treatment of the wormlike chain model (WLC) isused to analyze
experiments in which double-stranded DNA, tethered at one end, is stretched by a force …
experiments in which double-stranded DNA, tethered at one end, is stretched by a force …
Entropic elasticity of λ-phage DNA
20. Rat T9 cells were transfected by the calcium phosphate precipitation method with 1 jig of
pCMVEN10 complementary DNA (cDNA)(19) and 0.1 jig of pSV2neo (neomycin resistance …
pCMVEN10 complementary DNA (cDNA)(19) and 0.1 jig of pSV2neo (neomycin resistance …
[PDF][PDF] Interphase chromosomes undergo constrained diffusional motion in living cells
Background: Structural studies of fixed cells have revealed that interphase chromosomes are
highly organized into specific arrangements in the nucleus, and have led to a picture of the …
highly organized into specific arrangements in the nucleus, and have led to a picture of the …
Statistical mechanics of supercoiled DNA
The two strands of a closed circular DNA molecule possess as a topological invariant their
linking number. This property, combined with an appreciable twist elastic constant, causes the …
linking number. This property, combined with an appreciable twist elastic constant, causes the …
Self-organization of domain structures by DNA-loop-extruding enzymes
E Alipour, JF Marko - Nucleic acids research, 2012 - academic.oup.com
The long chromosomal DNAs of cells are organized into loop domains much larger in size
than individual DNA-binding enzymes, presenting the question of how formation of such …
than individual DNA-binding enzymes, presenting the question of how formation of such …
Prostate cancer: interobserver agreement and accuracy with the revised prostate imaging reporting and data system at multiparametric MR imaging
BG Muller, JH Shih, S Sankineni, J Marko… - Radiology, 2015 - pubs.rsna.org
Purpose To evaluate accuracy and interobserver variability with the use of the Prostate
Imaging Reporting and Data System (PI-RADS) version 2.0 for detection of prostate cancer at …
Imaging Reporting and Data System (PI-RADS) version 2.0 for detection of prostate cancer at …
Chromatin and lamin A determine two different mechanical response regimes of the cell nucleus
The cell nucleus must continually resist and respond to intercellular and intracellular mechanical
forces to transduce mechanical signals and maintain proper genome organization and …
forces to transduce mechanical signals and maintain proper genome organization and …