Molecular cloning and disease association of hepatitis G virus: a transfusion-transmissible agent

J Linnen, J Wages Jr, ZY Zhang-Keck, KE Fry… - Science, 1996 - science.org
An RNA virus, designated hepatitis G virus (HGV), was identified from the plasma of a
patient with chronic hepatitis. Extension from an immunoreactive complementary DNA clone …

[HTML][HTML] Rapid metagenomic identification of viral pathogens in clinical samples by real-time nanopore sequencing analysis

…, D Stryke, J Bouquet, S Somasekar, JM Linnen… - Genome medicine, 2015 - Springer
We report unbiased metagenomic detection of chikungunya virus (CHIKV), Ebola virus (EBOV),
and hepatitis C virus (HCV) from four human blood samples by MinION nanopore …

Virus and antibody dynamics in acute West Nile virus infection

…, RS Lanciotti, DJ Wright, JM Linnen… - The Journal of …, 2008 - academic.oup.com
Background . The dynamics of the early stages of West Nile virus (WNV) infection can be
assessed by follow-up studies of viremic blood donors. Methods . A total of 245 donors with …

Dengue viremia in blood donors identified by RNA and detection of dengue transfusion transmission during the 2007 dengue outbreak in Puerto Rico

SL Stramer, JM Linnen, JM Carrick, GA Foster… - …, 2012 - Wiley Online Library
BACKGROUND: In 2007, a total of 10,508 suspected dengue cases were reported in Puerto
Rico. Blood donations were tested for dengue virus (DENV) RNA and recipients of RNA‐…

Evidence for persistent low-level viremia in individuals who control human immunodeficiency virus in the absence of antiretroviral therapy

…, PW Hunt, R Hoh, SL Stramer, JM Linnen… - Journal of …, 2009 - Am Soc Microbiol
… Samples of known HIV viral load copy numbers (0, 1, 3, 10, 30, 100, and 300 copies/ml) were
tested with the TMA assay 20 times each by four different laboratory technicians (J. Linnen, …

[HTML][HTML] Screening the blood supply for West Nile virus RNA by nucleic acid amplification testing

…, LH Tobler, H Kamel, JM Linnen… - … England Journal of …, 2005 - Mass Medical Soc
Background The use of nucleic acid amplification tests of “minipools” of 16 samples to
screen blood donors for West Nile virus RNA began in July 2003. We report the yield and …

Seroprevalence of hepatitis E virus (HEV) and detection of HEV RNA with a transcription‐mediated amplification assay in blood donors from C atalonia (S pain)

…, M Koppelman, L Danzig, JM Linnen - …, 2015 - Wiley Online Library
Background Hepatitis E virus ( HEV ) is an emerging threat to the safety of blood transfusion.
The aim of this study was to determine HEV immunoglobulin ( Ig ) G and RNA prevalence in …

Dengue viremia in blood donors from Honduras, Brazil, and Australia

JM Linnen, E Vinelli, EC Sabino, LH Tobler… - …, 2008 - Wiley Online Library
BACKGROUND: Dengue fever and hemorrhagic disease are caused by four dengue virus (DENV)
serotypes (DENV‐1 to ‐4), mosquito‐borne flaviviruses with increasing incidence, …

Transfusion-transmitted dengue and associated clinical symptoms during the 2012 epidemic in Brazil

…, LC Oliveira, JM Linnen… - The Journal of …, 2016 - academic.oup.com
Background. A linked donor-recipient study was conducted during epidemics in 2 cities in
Brazil to investigate transfusion-transmitted (TT) dengue virus (DENV) by DENV RNA–positive …

Dengue virus in blood donations, Puerto Rico, 2005

H Mohammed, JM Linnen, JL Muñoz‐Jordán… - …, 2008 - Wiley Online Library
BACKGROUND: A single instance of transfusion‐transmitted dengue infection has been
reported. The high incidence of dengue in endemic countries, the high proportion of …