User profiles for J. Kugelman

Jeffrey Kugelman

- Verified email at mail.mil - Cited by 4797

Jason Kugelman

- Verified email at qut.edu.au - Cited by 404

[HTML][HTML] Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys

…, DK Nichols, JE Nuss, ER Nagle, JR Kugelman… - Nature, 2016 - nature.com
The most recent Ebola virus outbreak in West Africa, which was unprecedented in the number
of cases and fatalities, geographic distribution, and number of nations affected, highlights …

[HTML][HTML] Molecular evidence of sexual transmission of Ebola virus

SE Mate, JR Kugelman, TG Nyenswah… - … England Journal of …, 2015 - Mass Medical Soc
<p id="p001">A suspected case of sexual transmission from a male survivor of Ebola virus
disease (EVD) to his female partner (the patient in this report) occurred in Liberia in March …

[HTML][HTML] Recent successes in therapeutics for Ebola virus disease: no time for complacency

…, GF Palacios, JR Kugelman… - The Lancet Infectious …, 2020 - thelancet.com
The PALM trial in the Democratic Republic of the Congo identified a statistically significant
survival benefit for two monoclonal antibody-based therapeutics in the treatment of acute …

Virus genomes reveal factors that spread and sustained the Ebola epidemic

…, JA Hiscox, U Jah, JR Kugelman, D Liu, J Lu… - Nature, 2017 - nature.com
The 2013–2016 West African epidemic caused by the Ebola virus was of unprecedented
magnitude, duration and impact. Here we reconstruct the dispersal, proliferation and decline of …

[HTML][HTML] Ebola virus epidemiology, transmission, and evolution during seven months in Sierra Leone

…, JR Kugelman, CB Matranga, SM Winnicki, J Qu… - Cell, 2015 - cell.com
The 2013–2015 Ebola virus disease (EVD) epidemic is caused by the Makona variant of
Ebola virus (EBOV). Early in the epidemic, genome sequencing provided insights into virus …

[HTML][HTML] Genomic variability of monkeypox virus among humans, Democratic Republic of the Congo

JR Kugelman, SC Johnston… - Emerging infectious …, 2014 - ncbi.nlm.nih.gov
… Dr Kugelman is a biodefense research scientist and bioinformatician in the Center for
Genome Sciences at United States Army Medical Research Institute of Infectious Diseases. His …

[HTML][HTML] Possible sexual transmission of Ebola virus—Liberia, 2015

…, JT Ladner, MR Wiley, JR Kugelman… - … and Mortality Weekly …, 2015 - ncbi.nlm.nih.gov
In addition to patient A, survivor A reported recent unprotected vaginal intercourse with a
woman aged 45 years (contact A) with no history of illness. Intercourse with contact A occurred …

[HTML][HTML] A comparison of deep learning U-Net architectures for posterior segment OCT retinal layer segmentation

J Kugelman, J Allman, SA Read, SJ Vincent, J Tong… - Scientific reports, 2022 - nature.com
Deep learning methods have enabled a fast, accurate and automated approach for retinal
layer segmentation in posterior segment OCT images. Due to the success of semantic …

[PDF][PDF] Evolution and spread of Ebola virus in Liberia, 2014–2015

…, M Sanchez-Lockhart, FK Bolay, JR Kugelman… - Cell host & …, 2015 - cell.com
The 2013–present Western African Ebola virus disease (EVD) outbreak is the largest ever
recorded with >28,000 reported cases. Ebola virus (EBOV) genome sequencing has played …

[HTML][HTML] Automatic choroidal segmentation in OCT images using supervised deep learning methods

J Kugelman, D Alonso-Caneiro, SA Read… - Scientific reports, 2019 - nature.com
The analysis of the choroid in the eye is crucial for our understanding of a range of ocular
diseases and physiological processes. Optical coherence tomography (OCT) imaging provides …