[HTML][HTML] Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys
…, DK Nichols, JE Nuss, ER Nagle, JR Kugelman… - Nature, 2016 - nature.com
The most recent Ebola virus outbreak in West Africa, which was unprecedented in the number
of cases and fatalities, geographic distribution, and number of nations affected, highlights …
of cases and fatalities, geographic distribution, and number of nations affected, highlights …
[HTML][HTML] Molecular evidence of sexual transmission of Ebola virus
SE Mate, JR Kugelman, TG Nyenswah… - … England Journal of …, 2015 - Mass Medical Soc
<p id="p001">A suspected case of sexual transmission from a male survivor of Ebola virus
disease (EVD) to his female partner (the patient in this report) occurred in Liberia in March …
disease (EVD) to his female partner (the patient in this report) occurred in Liberia in March …
[HTML][HTML] Recent successes in therapeutics for Ebola virus disease: no time for complacency
…, GF Palacios, JR Kugelman… - The Lancet Infectious …, 2020 - thelancet.com
The PALM trial in the Democratic Republic of the Congo identified a statistically significant
survival benefit for two monoclonal antibody-based therapeutics in the treatment of acute …
survival benefit for two monoclonal antibody-based therapeutics in the treatment of acute …
Virus genomes reveal factors that spread and sustained the Ebola epidemic
The 2013–2016 West African epidemic caused by the Ebola virus was of unprecedented
magnitude, duration and impact. Here we reconstruct the dispersal, proliferation and decline of …
magnitude, duration and impact. Here we reconstruct the dispersal, proliferation and decline of …
[HTML][HTML] Ebola virus epidemiology, transmission, and evolution during seven months in Sierra Leone
…, JR Kugelman, CB Matranga, SM Winnicki, J Qu… - Cell, 2015 - cell.com
The 2013–2015 Ebola virus disease (EVD) epidemic is caused by the Makona variant of
Ebola virus (EBOV). Early in the epidemic, genome sequencing provided insights into virus …
Ebola virus (EBOV). Early in the epidemic, genome sequencing provided insights into virus …
[HTML][HTML] Genomic variability of monkeypox virus among humans, Democratic Republic of the Congo
JR Kugelman, SC Johnston… - Emerging infectious …, 2014 - ncbi.nlm.nih.gov
… Dr Kugelman is a biodefense research scientist and bioinformatician in the Center for
Genome Sciences at United States Army Medical Research Institute of Infectious Diseases. His …
Genome Sciences at United States Army Medical Research Institute of Infectious Diseases. His …
[HTML][HTML] Possible sexual transmission of Ebola virus—Liberia, 2015
In addition to patient A, survivor A reported recent unprotected vaginal intercourse with a
woman aged 45 years (contact A) with no history of illness. Intercourse with contact A occurred …
woman aged 45 years (contact A) with no history of illness. Intercourse with contact A occurred …
[HTML][HTML] A comparison of deep learning U-Net architectures for posterior segment OCT retinal layer segmentation
Deep learning methods have enabled a fast, accurate and automated approach for retinal
layer segmentation in posterior segment OCT images. Due to the success of semantic …
layer segmentation in posterior segment OCT images. Due to the success of semantic …
[PDF][PDF] Evolution and spread of Ebola virus in Liberia, 2014–2015
…, M Sanchez-Lockhart, FK Bolay, JR Kugelman… - Cell host & …, 2015 - cell.com
The 2013–present Western African Ebola virus disease (EVD) outbreak is the largest ever
recorded with >28,000 reported cases. Ebola virus (EBOV) genome sequencing has played …
recorded with >28,000 reported cases. Ebola virus (EBOV) genome sequencing has played …
[HTML][HTML] Automatic choroidal segmentation in OCT images using supervised deep learning methods
The analysis of the choroid in the eye is crucial for our understanding of a range of ocular
diseases and physiological processes. Optical coherence tomography (OCT) imaging provides …
diseases and physiological processes. Optical coherence tomography (OCT) imaging provides …