User profiles for J. Hussin
Julie HussinMontreal Heart Institute, University of Montreal Verified email at umontreal.ca Cited by 1478 |
[PDF][PDF] The way forward in sustainable construction: issues and challenges
Construction industry is one of the most significant industries that contribute toward socio-economic
growth especially to developing countries. The nature of the industry are fragmented, …
growth especially to developing countries. The nature of the industry are fragmented, …
[PDF][PDF] Mutations in centrosomal protein CEP152 in primary microcephaly families linked to MCPH4
DL Guernsey, H Jiang, J Hussin, M Arnold… - The American Journal of …, 2010 - cell.com
Primary microcephaly is a rare condition in which brain size is substantially diminished
without other syndromic abnormalities. Seven autosomal loci have been genetically mapped, …
without other syndromic abnormalities. Seven autosomal loci have been genetically mapped, …
Re-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice
The DNA-binding protein PRDM9 directs positioning of the double-strand breaks (DSBs)
that initiate meiotic recombination in mice and humans. Prdm9 is the only mammalian …
that initiate meiotic recombination in mice and humans. Prdm9 is the only mammalian …
[HTML][HTML] Implementing machine learning in interventional cardiology: the benefits are worth the trouble
…, R Cartier, R Ibrahim, T Modine, JG Hussin - Frontiers in …, 2021 - frontiersin.org
Driven by recent innovations and technological progress, the increasing quality and amount
of biomedical data coupled with the advances in computing power allowed for much …
of biomedical data coupled with the advances in computing power allowed for much …
[HTML][HTML] Multiscale PHATE identifies multimodal signatures of COVID-19
As the biomedical community produces datasets that are increasingly complex and high
dimensional, there is a need for more sophisticated computational tools to extract biological …
dimensional, there is a need for more sophisticated computational tools to extract biological …
The impact of recombination on human mutation load and disease
Recombination promotes genomic integrity among cells and tissues through double-strand
break repair, and is critical for gamete formation and fertility through a strict regulation of the …
break repair, and is critical for gamete formation and fertility through a strict regulation of the …
Recombination affects accumulation of damaging and disease-associated mutations in human populations
Many decades of theory have demonstrated that, in non-recombining systems, slightly
deleterious mutations accumulate non-reversibly 1 , potentially driving the extinction of many …
deleterious mutations accumulate non-reversibly 1 , potentially driving the extinction of many …
[HTML][HTML] Whole-exome sequencing reveals a rapid change in the frequency of rare functional variants in a founding population of humans
Whole-exome or gene targeted resequencing in hundreds to thousands of individuals has
shown that the majority of genetic variants are at low frequency in human populations. Rare …
shown that the majority of genetic variants are at low frequency in human populations. Rare …
SARS–CoV-2 receptor ACE2 gene is associated with hypertension and severity of COVID 19: interaction with sex, obesity, and smoking
…, AW Cowley, J Hussin, J Tremblay - American journal of …, 2021 - academic.oup.com
BACKGROUND Angiotensin-converting enzyme 2 (ACE2) has been identified as the entry
receptor for coronaviruses into human cells, including severe acute respiratory syndrome …
receptor for coronaviruses into human cells, including severe acute respiratory syndrome …
Diet networks: thin parameters for fat genomics
… where ej represents the embedding of a feature in XT, φ is a non-linear function and (We)j:
is the j-th row of We. This means that each feature is associated with the vector of values it …
is the j-th row of We. This means that each feature is associated with the vector of values it …