Introduction: Pompe disease is a rare, autosomal recessive disorder caused by deficiency
of the glycogen‐degrading lysosomal enzyme acid alpha‐glucosidase. Late‐onset Pompe …

… Acknowledgments A part of this work was done while J. Han was employed by CWI, the
Netherlands. … Han would like to thank Dr. E. Pauwels for granting the opportunity to work on this …

Small RNAs of 20–30 nucleotides can target both chromatin and transcripts, and thereby keep
both the genome and the transcriptome under extensive surveillance. Recent progress in …

Background—Sympathetic nerve activity is known to be important in ventricular
arrhythmogenesis, but there is little information on the relation between the distribution of cardiac …

Walking abnormalities are prominent in Duchenne muscular dystrophy (DMD). We modified
the 6‐minute walk test (6MWT) for use as an outcome measure in patients with DMD and …

Current methods of forcing end‐tidal P CO2 (P ETCO2 ) and P O2 (P ETO2 ) rely on breath‐by‐breath
adjustment of inspired gas concentrations using feedback loop algorithms. Such …

As telehealth plays an even greater role in global health care delivery, it will be increasingly
important to develop a strong evidence base of successful, innovative telehealth solutions …

In this study we used the 6‐minute walk distance (6MWD) to characterize ambulation over
time in Duchenne/Becker muscular dystrophy (DBMD). The 6MWD was assessed in 18 boys …

Background and Purpose— Blood oxygen level-dependent MRI (BOLD MRI) of hypercapnia-induced
changes in cerebral blood flow is an emerging technique for mapping …

Mammalian cells respond to endotoxic lipopolysaccharide (LPS) by activation of protein
kinase cascades that lead to new gene expression. A protein kinase, p38, that was tyrosine …