OBJECTIVE To examine the global prevalence and major risk factors for diabetic retinopathy
(DR) and vision-threatening diabetic retinopathy (VTDR) among people with diabetes. …

Peen J, Schoevers RA, Beekman AT, Dekker J. The current status of urban–rural differences
in psychiatric disorders. Objective: Reviews of urban–rural differences in psychiatric …

… Scheppers E, van Dongen E, Dekker J, Geertzen J and Dekker J. Potential barriers to the
use of health services among ethnic minorities: a review. Family Practice 2006; 23: 325–348. …

We describe Hi-C, a method that probes the three-dimensional architecture of whole genomes
by coupling proximity-based ligation with massively parallel sequencing. We constructed …

DNase I hypersensitive sites (DHSs) are markers of regulatory DNA and have underpinned
the discovery of all classes of cis-regulatory elements including enhancers, promoters, …

We describe an approach to detect the frequency of interaction between any two genomic
loci. Generation of a matrix of interaction frequencies between sites on the same or different …

In eukaryotes transcriptional regulation often involves multiple long-range elements and is
influenced by the genomic environment 1 . A prime example of this concerns the mouse X-…

The human and mouse genomes contain instructions that specify RNAs and proteins and
govern the timing, magnitude, and cellular context of their production. To better delineate these …

OBJECTIVES: Recently, an increasing number of systematic reviews have been published
in which the measurement properties of health status questionnaires are compared. For a …

Transcription factors control cell-specific gene expression programs through interactions
with diverse coactivators and the transcription apparatus. Gene activation may involve DNA …