User profiles for J. Coon

Joshua J. Coon

- Verified email at chem.wisc.edu - Cited by 33407

Jo Thompson Coon

- Verified email at exeter.ac.uk - Cited by 12457

The utility of ETD mass spectrometry in proteomic analysis

…, A Chi, JJ Coon, JEP Syka, J Shabanowitz… - … et Biophysica Acta (BBA …, 2006 - Elsevier
Mass spectrometry has played an integral role in the identification of proteins and their post-translational
modifications (PTM). However, analysis of some PTMs, such as phosphorylation…

[PDF][PDF] Large-scale multi-omic analysis of COVID-19 severity

…, S Swanson, DF Mosher, R Stewart, JJ Coon… - Cell systems, 2021 - cell.com
We performed RNA-seq and high-resolution mass spectrometry on 128 blood samples from
COVID-19-positive and COVID-19-negative patients with diverse disease severities and …

Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry

JEP Syka, JJ Coon, MJ Schroeder… - Proceedings of the …, 2004 - National Acad Sciences
Peptide sequence analysis using a combination of gas-phase ion/ion chemistry and tandem
mass spectrometry (MS/MS) is demonstrated. Singly charged anthracene anions transfer an …

Panax ginseng

JT Coon, E Ernst - Drug safety, 2002 - Springer
Panax ginseng CA Meyer is a perennial herb native to Korea and China and has been used
as an herbal remedy in eastern Asia for thousands of years. Modern therapeutic claims refer …

[HTML][HTML] Effectiveness of mindfulness-based stress reduction and mindfulness based cognitive therapy in vascular disease: A systematic review and meta-analysis of …

…, R Whear, LR Rodgers, A Bethel, JT Coon… - Journal of …, 2014 - Elsevier
Objective To determine the effectiveness of mindfulness-based stress reduction (MBSR) and
mindfulness-based cognitive therapy (MBCT) on psychological and physical outcomes for …

A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

…, RV Kondratov, K Christov-Tselkov, JS Coon… - Science, 1999 - science.org
Chemotherapy and radiation therapy for cancer often have severe side effects that limit their
efficacy. Because these effects are in part determined by p53-mediated apoptosis, …

[HTML][HTML] Parallel reaction monitoring for high resolution and high mass accuracy quantitative, targeted proteomics

…, JD Russell, DJ Bailey, MS Westphall, JJ Coon - Molecular & cellular …, 2012 - ASBMB
Selected reaction monitoring on a triple quadrupole mass spectrometer is currently experiencing
a renaissance within the proteomics community for its, as yet, unparalleled ability to …

Formic-acid-induced depolymerization of oxidized lignin to aromatics

A Rahimi, A Ulbrich, JJ Coon, SS Stahl - Nature, 2014 - nature.com
Lignin is a heterogeneous aromatic biopolymer that accounts for nearly 30% of the organic
carbon on Earth 1 and is one of the few renewable sources of aromatic chemicals 2 . As the …

[PDF][PDF] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome

…, TA Prolla, F Assadi-Porter, S Roy, JM Denu, JJ Coon - Molecular cell, 2013 - cell.com
Calorie restriction (CR) extends life span in diverse species. Mitochondria play a key role in
CR adaptation; however, the molecular details remain elusive. We developed and applied a …

Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry

…, C Huttenhower, LY Geer, JJ Coon… - Proceedings of the …, 2007 - National Acad Sciences
We present a strategy for the analysis of the yeast phosphoproteome that uses endo-Lys C
as the proteolytic enzyme, immobilized metal affinity chromatography for phosphopeptide …