Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Schizophrenia has a heritability of 60–80% 1 , much of which is attributable to common risk
alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with …
alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with …
[HTML][HTML] Role of carnitine and its derivatives in the development and management of type 2 diabetes
Type 2 diabetes is a highly prevalent chronic metabolic disorder characterized by hyperglycemia
and associated with several complications such as retinopathy, hyperlipidemia and …
and associated with several complications such as retinopathy, hyperlipidemia and …
Ancient human genomes suggest three ancestral populations for present-day Europeans
… , O base is a reference outgroup, and O j is the set of other outgroups (ancient DNA samples,
Onge, Karitiana, and Mbuti). The rank of the (i, j) matrix reflects the minimum number of …
Onge, Karitiana, and Mbuti). The rank of the (i, j) matrix reflects the minimum number of …
[PDF][PDF] Modeling linkage disequilibrium increases accuracy of polygenic risk scores
…, M Begemann, RA Belliveau, J Bene… - The american journal of …, 2015 - cell.com
Polygenic risk scores have shown great promise in predicting complex disease risk and will
become more accurate as training sample sizes increase. The standard approach for …
become more accurate as training sample sizes increase. The standard approach for …
[PDF][PDF] Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases
…, M Begemann, RA Belliveau, J Bene… - The American Journal of …, 2014 - cell.com
Regulatory and coding variants are known to be enriched with associations identified by
genome-wide association studies (GWASs) of complex disease, but their contributions to trait …
genome-wide association studies (GWASs) of complex disease, but their contributions to trait …
Use of the CNDO method in spectroscopy. I. Benzene, pyridine, and the diazines
JD Bene, HH Jaffe - The Journal of Chemical Physics, 1968 - pubs.aip.org
… where the energies and the J and K integrals are defined as above. Since, in the case of
benzene, the values of €i, and the values of E/' are approximately equal for each of the first …
benzene, the values of €i, and the values of E/' are approximately equal for each of the first …
[PDF][PDF] Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes
…, RA Belliveau, F Bellivier, S Bender, J Bene… - Cell, 2018 - cell.com
Schizophrenia and bipolar disorder are two distinct diagnoses that share symptomology.
Understanding the genetic factors contributing to the shared and disorder-specific symptoms …
Understanding the genetic factors contributing to the shared and disorder-specific symptoms …
[BOOK][B] Trees, food and people: land management in the tropics
JG Bene, HW Beall, A Côté - 1977 - idl-bnc-idrc.dspacedirect.org
… The tragedy is that the export of choice timber from the humid zone benefits only a few people
in developing countries, and not enough revenue is generated to pay for reforestation or to …
in developing countries, and not enough revenue is generated to pay for reforestation or to …
A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts
…, SA Bacanu, M Begemann, RA Belliveau Jr, J Bene… - Biological …, 2021 - Elsevier
… of an individual, j, as a weighted sum of SNP allele counts: ∑ i = 1 m b ˆ i x i j , where m is …
, x i j is a count of the number (0, 1, or 2) of trait-associated alleles of SNP i in individual j. We …
, x i j is a count of the number (0, 1, or 2) of trait-associated alleles of SNP i in individual j. We …
Bullous pemphigoid and dipeptidyl peptidase IV inhibitors: a case–noncase study in the French Pharmacovigilance Database
J Béné, G Moulis, I Bennani, M Auffret… - British Journal of …, 2016 - academic.oup.com
Background Inhibitors of dipeptidyl peptidase (DPP)‐IV have been suspected in the onset of
bullous pemphigoid for several years now. However, comparative studies assessing the link …
bullous pemphigoid for several years now. However, comparative studies assessing the link …