Porcine reproductive and respiratory syndrome (PRRS) virus appeared 20 years ago as the
cause of a new disease in swine. Today PRRS is the most significant swine disease …

The apicomplexan Cryptosporidium parvum is an intestinal parasite that affects healthy
humans and animals, and causes an unrelenting infection in immunocompromised individuals …

… (J) Summary scores for cellular proliferation and neutrophil distribution. Data are
representative of 2 independent experiments (A–C, and G–I) or were pooled from 2 independent …

Temporal control of development is an important aspect of pattern formation that awaits
complete molecular analysis. We identified lin-57 as a member of the C. elegans heterochronic …

CRISPR-Cas9-Cytidine deaminase fusion enzymes—termed “base editors”—allow targeted
editing of genomic deoxycytidine to deoxythymidine (C:G→T:A) without the need for double-…

The apicomplexans Plasmodium and Cryptosporidium have developed distinctive adaptations
via lineage-specific gene loss and gene innovation in the process of diverging from a …

CFTR, the cystic fibrosis (CF) gene, encodes for the CFTR protein that plays an essential
role in anion regulation and tissue homeostasis of various epithelia. In the gastrointestinal (GI) …

Identification of cancer driver gene mutations is crucial for advancing cancer therapeutics.
Due to the overwhelming number of passenger mutations in the human tumor genome, it is …

Objectives The purpose of this study was to determine the level of heterogeneity in high
grade serous ovarian cancer (HGSOC) by analyzing RNA expression in single epithelial and …

Microglia are considered both pathogenic and protective during recovery from demyelination,
but their precise role remains ill defined. Here, using an inhibitor of colony stimulating …