User profiles for J. T. Walters
James WaltersCardiff University Verified email at cf.ac.uk Cited by 43718 |
Genome-wide association analysis identifies 13 new risk loci for schizophrenia
Schizophrenia is an idiopathic mental disorder with a heritable component and a substantial
public health impact. We conducted a multi-stage genome-wide association study (GWAS) …
public health impact. We conducted a multi-stage genome-wide association study (GWAS) …
Rare coding variants in ten genes confer substantial risk for schizophrenia
Rare coding variation has historically provided the most direct connections between gene
function and disease pathogenesis. By meta-analysing the whole exomes of 24,248 …
function and disease pathogenesis. By meta-analysing the whole exomes of 24,248 …
[HTML][HTML] Phenotype, function, and differentiation potential of human monocyte subsets
LB Boyette, C Macedo, K Hadi, BD Elinoff, JT Walters… - PloS one, 2017 - journals.plos.org
Human monocytes have been grouped into classical (CD14 ++ CD16 − ), non-classical (CD14
dim CD16 ++ ), and intermediate (CD14 ++ CD16 + ) subsets. Documentation of normal …
dim CD16 ++ ), and intermediate (CD14 ++ CD16 + ) subsets. Documentation of normal …
Phenotypic manifestation of genetic risk for schizophrenia during adolescence in the general population
Importance Schizophrenia is a highly heritable, polygenic condition characterized by a relatively
diverse phenotype and frequent comorbid conditions, such as anxiety and depression. …
diverse phenotype and frequent comorbid conditions, such as anxiety and depression. …
[HTML][HTML] Schizophrenia risk conferred by rare protein-truncating variants is conserved across diverse human populations
Schizophrenia (SCZ) is a chronic mental illness and among the most debilitating conditions
encountered in medical practice. A recent landmark SCZ study of the protein-coding regions …
encountered in medical practice. A recent landmark SCZ study of the protein-coding regions …
Basin-scale wind transport during the MILAGRO field campaign and comparison to climatology using cluster analysis
…, SJ Paech, D Phillips, JT Walters… - Atmospheric …, 2008 - acp.copernicus.org
The MILAGRO field campaign was a multi-agency international collaborative project to evaluate
the regional impacts of the Mexico City air pollution plume as a means of understanding …
the regional impacts of the Mexico City air pollution plume as a means of understanding …
Exome arrays capture polygenic rare variant contributions to schizophrenia
AL Richards, G Leonenko, JT Walters… - Human molecular …, 2016 - academic.oup.com
Schizophrenia is a highly heritable disorder. Genome-wide association studies based largely
on common alleles have identified over 100 schizophrenia risk loci, but it is also evident …
on common alleles have identified over 100 schizophrenia risk loci, but it is also evident …
Long-term effects of alemtuzumab on regulatory and memory T-cell subsets in kidney transplantation
C Macedo, JT Walters, EA Orkis, K Isse… - …, 2012 - journals.lww.com
Background. Induction with lymphocyte-depleting antibodies is routinely used to prevent
rejection but often skews T cells toward memory. It is not fully understood which memory and …
rejection but often skews T cells toward memory. It is not fully understood which memory and …
Positive surface temperature feedback in the stable nocturnal boundary layer
JT Walters, RT McNider, X Shi… - Geophysical …, 2007 - Wiley Online Library
The techniques of nonlinear analysis are used to examine the behavior of the stable nocturnal
boundary layer (SNBL) when it is subjected to changes in incoming radiation or in surface …
boundary layer (SNBL) when it is subjected to changes in incoming radiation or in surface …
[HTML][HTML] Analysis of exome sequence in 604 trios for recessive genotypes in schizophrenia
E Rees, G Kirov, JT Walters, AL Richards… - Translational …, 2015 - nature.com
Genetic associations involving both rare and common alleles have been reported for
schizophrenia but there have been no systematic scans for rare recessive genotypes using fully …
schizophrenia but there have been no systematic scans for rare recessive genotypes using fully …