User profiles for J. P. Casas
JP Casas, MD, PhDBiomarker Development / Translational Medicine. Novartis Institute for Biomed Research Verified email at novartis.com Cited by 83091 |
Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis
Background Women with gestational diabetes are at increased risk of developing type 2
diabetes, but the risk and time of onset have not been fully quantified. We therefore did a …
diabetes, but the risk and time of onset have not been fully quantified. We therefore did a …
Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis
Objective To quantify the risk of future cardiovascular diseases, cancer, and mortality after
pre-eclampsia. Design Systematic review and meta-analysis. Data sources Embase and …
pre-eclampsia. Design Systematic review and meta-analysis. Data sources Embase and …
Statins for the primary prevention of cardiovascular disease
… The trials dated from 1994 to 2006 and were conducted world‐wide, mainly in industrially
developed countries (Japan, USA and Europe). Twelve trials recruited patients with specific …
developed countries (Japan, USA and Europe). Twelve trials recruited patients with specific …
[HTML][HTML] Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement …
…, AC Carlsson, MJ Carvalho, FF Casanueva, JP Casas… - The lancet, 2017 - thelancet.com
Background Underweight, overweight, and obesity in childhood and adolescence are associated
with adverse health consequences throughout the life-course. Our aim was to estimate …
with adverse health consequences throughout the life-course. Our aim was to estimate …
[HTML][HTML] Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4· 4 million participants
Background One of the global targets for non-communicable diseases is to halt, by 2025,
the rise in the age-standardised adult prevalence of diabetes at its 2010 levels. We aimed to …
the rise in the age-standardised adult prevalence of diabetes at its 2010 levels. We aimed to …
[HTML][HTML] Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19· 1 million participants
…, AC Carlsson, MJ Carvalho, FF Casanueva, JP Casas… - The Lancet, 2017 - thelancet.com
Background Raised blood pressure is an important risk factor for cardiovascular diseases
and chronic kidney disease. We estimated worldwide trends in mean systolic and mean …
and chronic kidney disease. We estimated worldwide trends in mean systolic and mean …
Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts
Background— High-throughput profiling of circulating metabolites may improve cardiovascular
risk prediction over established risk factors. Methods and Results— We applied …
risk prediction over established risk factors. Methods and Results— We applied …
[HTML][HTML] PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study
Background Statin treatment and variants in the gene encoding HMG-CoA reductase are
associated with reductions in both the concentration of LDL cholesterol and the risk of coronary …
associated with reductions in both the concentration of LDL cholesterol and the risk of coronary …
[HTML][HTML] Adherence to physical activity guidelines in older adults, using objectively measured physical activity in a population-based study
Background Physical activity (PA) levels in older adults decline with age. The prevalence
and correlates of adherence to current UK PA guidelines in older adults has not been studied …
and correlates of adherence to current UK PA guidelines in older adults has not been studied …
[PDF][PDF] Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip
Blood lipids are important cardiovascular disease (CVD) risk factors with both genetic and
environmental determinants. The Whitehall II study (n = 5592) was genotyped with the gene-…
environmental determinants. The Whitehall II study (n = 5592) was genotyped with the gene-…