User profiles for J. P. Casas

JP Casas, MD, PhD

Biomarker Development / Translational Medicine. Novartis Institute for Biomed Research
Verified email at novartis.com
Cited by 83091

Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis

L Bellamy, JP Casas, AD Hingorani, D Williams - The Lancet, 2009 - thelancet.com
Background Women with gestational diabetes are at increased risk of developing type 2
diabetes, but the risk and time of onset have not been fully quantified. We therefore did a …

Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis

L Bellamy, JP Casas, AD Hingorani, DJ Williams - Bmj, 2007 - bmj.com
Objective To quantify the risk of future cardiovascular diseases, cancer, and mortality after
pre-eclampsia. Design Systematic review and meta-analysis. Data sources Embase and …

Statins for the primary prevention of cardiovascular disease

…, M Burke, GD Smith, JP Casas… - Cochrane database …, 2011 - cochranelibrary.com
… The trials dated from 1994 to 2006 and were conducted world‐wide, mainly in industrially
developed countries (Japan, USA and Europe). Twelve trials recruited patients with specific …

[HTML][HTML] Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement …

…, AC Carlsson, MJ Carvalho, FF Casanueva, JP Casas… - The lancet, 2017 - thelancet.com
Background Underweight, overweight, and obesity in childhood and adolescence are associated
with adverse health consequences throughout the life-course. Our aim was to estimate …

[HTML][HTML] Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4· 4 million participants

…, AC Carlsson, MJ Carvalho, FF Casanueva, JP Casas… - The lancet, 2016 - thelancet.com
Background One of the global targets for non-communicable diseases is to halt, by 2025,
the rise in the age-standardised adult prevalence of diabetes at its 2010 levels. We aimed to …

[HTML][HTML] Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19· 1 million participants

…, AC Carlsson, MJ Carvalho, FF Casanueva, JP Casas… - The Lancet, 2017 - thelancet.com
Background Raised blood pressure is an important risk factor for cardiovascular diseases
and chronic kidney disease. We estimated worldwide trends in mean systolic and mean …

Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts

…, RS Vasan, OT Raitakari, RE Gerszten, JP Casas… - Circulation, 2015 - Am Heart Assoc
Background— High-throughput profiling of circulating metabolites may improve cardiovascular
risk prediction over established risk factors. Methods and Results— We applied …

[HTML][HTML] PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

…, MD Ritchie, FW Asselbergs, JP Casas… - The lancet Diabetes & …, 2017 - thelancet.com
Background Statin treatment and variants in the gene encoding HMG-CoA reductase are
associated with reductions in both the concentration of LDL cholesterol and the risk of coronary …

[HTML][HTML] Adherence to physical activity guidelines in older adults, using objectively measured physical activity in a population-based study

…, IM Lee, M Choi, A Amuzu, C Gutierrez, JP Casas… - BMC public health, 2014 - Springer
Background Physical activity (PA) levels in older adults decline with age. The prevalence
and correlates of adherence to current UK PA guidelines in older adults has not been studied …

[PDF][PDF] Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip

…, TR Gaunt, J Pallas, R Lovering, K Li, JP Casas… - The American journal of …, 2009 - cell.com
Blood lipids are important cardiovascular disease (CVD) risk factors with both genetic and
environmental determinants. The Whitehall II study (n = 5592) was genotyped with the gene-…