[PDF][PDF] GA4GH: International policies and standards for data sharing across genomic research and healthcare

…, JS Hsu, JP Hubaux, SE Hunt, A Husami, JO Jacobsen… - Cell genomics, 2021 - cell.com
The Global Alliance for Genomics and Health (GA4GH) aims to accelerate biomedical
advances by enabling the responsible sharing of clinical and genomic data through both …

Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium

TF Meehan, N Conte, DB West, JO Jacobsen… - Nature …, 2017 - nature.com
Although next-generation sequencing has revolutionized the ability to associate variants with
human diseases, diagnostic rates and development of new therapies are still limited by a …

Lamina emergent torsional (LET) joint

JO Jacobsen, G Chen, LL Howell… - Mechanism and Machine …, 2009 - Elsevier
Part of the challenge in designing compliant mechanisms is finding suitable joints that provide
the needed motion and force–deflection characteristics. The Lamina Emergent Torsional (…

Lamina emergent mechanisms and their basic elements

JO Jacobsen, BG Winder, LL Howell, SP Magleby - 2010 - asmedigitalcollection.asme.org
Lamina emergent mechanisms (LEMs) are fabricated from planar materials (lamina) and
have motion that emerges out of the fabrication plane. LEMs provide an opportunity to create …

[HTML][HTML] ALS2/Alsin regulates Rac-PAK signaling and neurite outgrowth

…, S Ackerley, J Brownlees, JON Jacobsen… - Journal of biological …, 2005 - ASBMB
Rac and its downstream effectors p21-activated kinase (PAK) family kinases regulate actin
dynamics within growth cones to control neurite outgrowth during development. The activity of …

Taking fourth-generation warfare to the skies? An empirical exploration of non-state actors' use of weaponized unmanned aerial vehicles (UAVs—'drones')

H Haugstvedt, JO Jacobsen - Perspectives on terrorism, 2020 - JSTOR
Recent events in and outside of conflict zones have raised apprehensions about the threat
that Unmanned Aerial Vehicles (UAVs) might pose to modern societies. There have been …

Charcot–Marie–Tooth disease neurofilament mutations disrupt neurofilament assembly and axonal transport

…, S Ackerley, AJ Grierson, NJO Jacobsen… - Human molecular …, 2002 - academic.oup.com
Charcot–Marie–Tooth disease (CMT) is the most common inherited disorder of the peripheral
nervous system, and mutations in neurofilaments have been linked to some forms of CMT. …

ATP2A2 Mutations in Darier's Disease and Their Relationship to Neuropsychiatric Phenotypes

NJO Jacobsen, I Lyons, B Hoogendoorn… - Human molecular …, 1999 - academic.oup.com
Darier's disease (DD) is a rare, dominantly inherited disorder that affects the skin producing
a variety of types of lesion. Close examination of lesional DD skin shows the presence of …

Components for the design of lamina emergent mechanisms

JO Jacobsen, LL Howell… - ASME …, 2007 - asmedigitalcollection.asme.org
This paper presents components for lamina emergent mechanism (LEM) that can be used
as building blocks to create mechanisms capable of more complex motion. As the name …

Auftragstaktik in the Norwegian armed forces

A Offerdal, JO Jacobsen - Defense Analysis, 1993 - Taylor & Francis
Every organization is facing a seemingly insoluble dilemma between the need for central
steering and control on the one hand and the need for local autonomy and initiative on the …