[HTML][HTML] Critical assessment of metagenome interpretation—a benchmark of metagenomics software

…, SJ Sørensen, BKH Chia, B Denis, JL Froula… - Nature …, 2017 - nature.com
Methods for assembly, taxonomic profiling and binning are key to interpreting metagenome
data, but a lack of consensus about benchmarking complicates performance assessment. …

Comparative metagenomics and population dynamics of the gut microbiota in mother and infant

…, JV Kuehl, JL Froula, JL Morgan… - Genome biology and …, 2010 - academic.oup.com
Colonization of the gastrointestinal tract (GIT) of human infants with a suitable microbial
community is essential for numerous aspects of health, but the progression of events by which …

Validation of two ribosomal RNA removal methods for microbial metatranscriptomics

S He, O Wurtzel, K Singh, JL Froula, S Yilmaz… - Nature …, 2010 - nature.com
The predominance of rRNAs in the transcriptome is a major technical challenge in sequence-based
analysis of cDNAs from microbial isolates and communities. Several approaches …

Quinolone antibiotics in therapy of experimental pneumococcal meningitis in rabbits

R Nau, T Schmidt, K Kaye, JL Froula… - Antimicrobial agents …, 1995 - Am Soc Microbiol
Using a rabbit model of pneumococcal meningitis, we compared the pharmacokinetics and
bactericidal activities in cerebrospinal fluid (CSF) of older (ciprofloxacin, ofloxacin) and …

[HTML][HTML] Generation of long insert pairs using a Cre-LoxP Inverse PCR approach

Z Peng, Z Zhao, N Nath, JL Froula, A Clum, T Zhang… - PloS one, 2012 - journals.plos.org
Large insert mate pair reads have a major impact on the overall success of de novo assembly
and the discovery of inherited and acquired structural variants. The positional information …

[HTML][HTML] Selection against spurious promoter motifs correlates with translational efficiency across bacteria

JL Froula, MP Francino - PLoS One, 2007 - journals.plos.org
Because binding of RNAP to misplaced sites could compromise the efficiency of transcription,
natural selection for the optimization of gene expression should regulate the distribution of …

[HTML][HTML] Flying focus: Spatial and temporal control of intensity for laser-based applications

DH Froula, JP Palastro, D Turnbull, A Davies… - Physics of …, 2019 - pubs.aip.org
An advanced focusing scheme, called a “flying focus,” uses a chromatic focusing system
combined with a broadband laser pulse with its colors arranged in time to propagate a high …

Observation of ion heating by stimulated-Brillouin-scattering-driven ion-acoustic waves using Thomson scattering

DH Froula, L Divol, HA Baldis, RL Berger… - Physics of …, 2002 - pubs.aip.org
Thomson-scattering measurements of the growth of ion-acoustic waves are obtained from
well-characterized multi-ion-species plasmas consisting of gold and beryllium. Simultaneously…

Benchmark data sets, software results and reference data for the first CAMI challenge

…, BKH Chia, B Denis, JL Froula… - GigaScience …, 2017 - pub.uni-bielefeld.de
Benchmark data sets, software results and reference data for the first CAMI challenge
Universität Bielefeld Universität Bielefeld Click a name to choose. Click to show more. PUB …

Experimental basis for laser-plasma interactions in ignition hohlraums at the National Ignition Facility

DH Froula, L Divol, RA London, RL Berger… - Physics of …, 2010 - pubs.aip.org
A series of laser-plasma interaction experiments is presented using gas-filled hohlraums
that shed light on the behavior of stimulated Raman scattering and stimulated Brillouin …