Human intervention studies have provided clear evidence that dietary polyphenols (eg,
flavonoids—eg, flavonols—and isoflavones) are at least partly absorbed and that they have the …

Flavonoids are components of fruit and vegetables that may be beneficial in the prevention
of disease such as cancer and cardiovascular diseases. Their beneficial effects will be …

Medical noncompliance has been identified as a major public health problem that imposes a
considerable financial burden upon modern health care systems. There is a large research …

Background The comparative effectiveness of treatments for prostate cancer that is detected
by prostate-specific antigen (PSA) testing remains uncertain. Methods We compared active …

Background Between 1999 and 2009 in the United Kingdom, 82,429 men between 50 and
69 years of age received a prostate-specific antigen (PSA) test. Localized prostate cancer …

Prostate cancer is the most common cancer affecting males in developed countries. It shows
consistent evidence of familial aggregation, but the causes of this aggregation are mostly …

Background Robust data on patient-reported outcome measures comparing treatments for
clinically localized prostate cancer are lacking. We investigated the effects of active monitoring…

A large quantity of research concerning issues of patient compliance with medications has
been produced in recent years. The assumption in much of this work is that patients have little …

Genome-wide association studies (GWAS) and fine-mapping efforts to date have identified
more than 100 prostate cancer (PrCa)-susceptibility loci. We meta-analyzed genotype data …

Prostate cancer is the most frequently diagnosed cancer in males in developed countries.
To identify common prostate cancer susceptibility alleles, we genotyped 211,155 SNPs on a …