User profiles for J. J. Lee

J. Jack Lee

- Verified email at mdanderson.org - Cited by 68943

James J. Lee

- Verified email at umn.edu - Cited by 21049

Jenny J. Lee

- Verified email at arizona.edu - Cited by 7533

Wave-induced oscillations in harbours of arbitrary geometry

JJ Lee - Journal of fluid mechanics, 1971 - cambridge.org
… boundary is sectionally smooth the following expression can be obtained (see Lee (1 969)
for the derivation of this expression and also for the case of a boundary with sharp corners). …

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

H Valadi, K Ekström, A Bossios, M Sjöstrand, JJ Lee… - Nature cell …, 2007 - nature.com
Exosomes are vesicles of endocytic origin released by many cells. These vesicles can mediate
communication between cells, facilitating processes such as antigen presentation. Here, …

[HTML][HTML] PD-1 blockade in tumors with mismatch-repair deficiency

…, GA Fisher, TS Crocenzi, JJ Lee… - … England Journal of …, 2015 - Mass Medical Soc
Background Somatic mutations have the potential to encode “non-self” immunogenic antigens.
We hypothesized that tumors with a large number of somatic mutations due to mismatch-…

Second-generation PLINK: rising to the challenge of larger and richer datasets

…, LCAM Tellier, S Vattikuti, SM Purcell, JJ Lee - …, 2015 - academic.oup.com
… James J Lee James J Lee … Christopher C Chang, Carson C Chow, Laurent CAM Tellier,
Shashaank Vattikuti, Shaun M Purcell, James J Lee, Second-generation PLINK: rising to the …

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

…, A Zaheer, GA Fisher, TS Crocenzi, JJ Lee… - Science, 2017 - science.org
The genomes of cancers deficient in mismatch repair contain exceptionally high numbers of
somatic mutations. In a proof-of-concept study, we previously showed that colorectal …

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

JJ Lee, R Wedow, A Okbay, E Kong, O Maghzian… - Nature …, 2018 - nature.com
Here we conducted a large-scale genetic association analysis of educational attainment in
a sample of approximately 1.1 million individuals and identify 1,271 independent genome-…

Genome-wide association study identifies 74 loci associated with educational attainment

A Okbay, JP Beauchamp, MA Fontana, JJ Lee, TH Pers… - Nature, 2016 - nature.com
Educational attainment is strongly influenced by social and other environmental factors, but
genetic factors are estimated to account for at least 20% of the variation across individuals 1. …

Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer

…, H Sugimoto, S Yang, CF Ruivo, SA Melo, JJ Lee… - Nature, 2017 - nature.com
The mutant form of the GTPase KRAS is a key driver of pancreatic cancer but remains a
challenging therapeutic target. Exosomes are extracellular vesicles generated by all cells, and …

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

…, J Yin, L Zuccolo, LJ Bierut, K Hveem, JJ Lee… - Nature …, 2019 - nature.com
Tobacco and alcohol use are leading causes of mortality that influence risk for many complex
diseases and disorders 1 . They are heritable 2 , 3 and etiologically related 4 , 5 behaviors …

Welcome to America? International student perceptions of discrimination

JJ Lee, C Rice - Higher education, 2007 - Springer
… Besides shedding light on dissatisfaction and discriminatory experiences as a reason for
declining enrollments (Lee, 2005), this study identifies student perceptions of discrimination …