Genome-wide association studies have identified hundreds of genetic variants associated
with complex human diseases and traits, and have provided valuable insights into their …

The proportions of people with type 2 diabetes and obesity have increased throughout Asia,
and the rate of increase shows no sign of slowing. People in Asia tend to develop diabetes …

The inflammatory bowel diseases Crohn's disease and ulcerative colitis are common, chronic
disorders that cause abdominal pain, diarrhea, and gastrointestinal bleeding. To identify …

Genome-wide association studies efficiently and powerfully assay common genetic variation.
The application of these studies to Crohn's disease has provided insight into the …

Crohn's disease is a chronic inflammatory disorder of the gastrointestinal tract, which is
thought to result from the effect of environmental factors in a genetically predisposed host. A …

Crohn’s disease and ulcerative colitis, the two common forms of inflammatory bowel disease
(IBD), affect over 2.5 million people of European ancestry, with rising prevalence in other …

Several risk factors for Crohn's disease have been identified in recent genome-wide association
studies. To advance gene discovery further, we combined data from three studies on …

We undertook a meta-analysis of six Crohn's disease genome-wide association studies (GWAS)
comprising 6,333 affected individuals (cases) and 15,056 controls and followed up the …

We present a genome-wide association study of ileal Crohn disease and two independent
replication studies that identify several new regions of association to Crohn disease. …

Genome-wide association studies and candidate gene studies in ulcerative colitis have
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis genome-…