Publisher Summary This chapter provides a framework for understanding the way permanent
heritable damage in cellular DNA results from exposure to ionizing radiation. If the …

The availability of intense electromagnetic fields produced by lasers has stimulated
experimental and theoretical investigations of nonlinear optical phenomena such as second-…

Ionizing radiation causes both singly and multiply damaged sites in DNA when the range of
radical migration is limited by the presence of hydroxyl radical scavengers (eg within cells). …

In the first paper in this section, authors from the Mayo Clinic describe their experience and
15‐year outcomes in the controversial subject of radical prostatectomy in patients with …

To date, anti-CTLA-4 (ipilimumab) or anti-PD-1 (nivolumab) monotherapy has not been
demonstrated to be of substantial clinical benefit in patients with prostate cancer. To identify …

Background Prostate MRI is used widely in clinical care for guiding tissue sampling, active
surveillance, and staging. The Prostate Imaging Reporting and Data System (PI-RADS) helps …

Cell killing by ionizing radiation has been shown to be caused by hydroxyl free radicals
formed by water radiolysis. We have previously suggested that the killing is not caused by …

… JF WARD, Deoxynucleotides-Models for studying mechanisms of strand breakage in DNA.
I… JF WARD and I. Kuo, Strand breaks, base release, and post-irradiation charges in DNA y-ir…

Purpose : We compare the morbidity, mortality, hospitalization and urethral catheter time of
contemporary transurethral prostatectomy to historical series, and evaluate recent trends in …

Purpose : Information regarding the clinical impact of delayed (5 years or greater) biochemical
failure (BF) after radical prostatectomy (RP) is lacking. We undertook an investigation to …