User profiles for J. E. Osorio
 | JORGE OSORIOProfessor Verified email at wisc.edu Cited by 10188 |
[HTML][HTML] SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters
The recent emergence of B.1.1.529, the Omicron variant 1 , 2 , has raised concerns of
escape from protection by vaccines and therapeutic antibodies. A key test for potential …
escape from protection by vaccines and therapeutic antibodies. A key test for potential …
[HTML][HTML] A rhesus macaque model of Asian-lineage Zika virus infection
Infection with Asian-lineage Zika virus (ZIKV) has been associated with Guillain–Barré
syndrome and fetal abnormalities, but the underlying mechanisms remain poorly understood. …
syndrome and fetal abnormalities, but the underlying mechanisms remain poorly understood. …
Vaccine-induced systemic and mucosal T cell immunity to SARS-CoV-2 viral variants
The first-generation COVID-19 vaccines have been effective in mitigating severe illness and
hospitalization, but recurring waves of infections are associated with the emergence of …
hospitalization, but recurring waves of infections are associated with the emergence of …
[HTML][HTML] Chloroquine, an endocytosis blocking agent, inhibits Zika virus infection in different cell models
Zika virus (ZIKV) infection in utero might lead to microcephaly and other congenital defects.
Since no specific therapy is available thus far, there is an urgent need for the discovery of …
Since no specific therapy is available thus far, there is an urgent need for the discovery of …
[HTML][HTML] Characterization of lethal Zika virus infection in AG129 mice
Background Mosquito-borne Zika virus (ZIKV) typically causes a mild and self-limiting illness
known as Zika fever, which often is accompanied by maculopapular rash, headache, and …
known as Zika fever, which often is accompanied by maculopapular rash, headache, and …
Chikungunya virus and prospects for a vaccine
In 2004, chikungunya virus (CHIKV) re-emerged from East Africa to cause devastating
epidemics of debilitating and often chronic arthralgia that have affected millions of people in the …
epidemics of debilitating and often chronic arthralgia that have affected millions of people in the …
[HTML][HTML] The wMel strain of Wolbachia Reduces Transmission of Zika virus by Aedes aegypti
Zika virus (ZIKV) is causing an explosive outbreak of febrile disease in the Americas. There
are no effective antiviral therapies or licensed vaccines for this virus and mosquito control …
are no effective antiviral therapies or licensed vaccines for this virus and mosquito control …
[HTML][HTML] Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques
…, EL Mohr, S Capuano III, AF Tarantal, JE Osorio… - PLoS …, 2017 - journals.plos.org
Infection with Zika virus (ZIKV) is associated with human congenital fetal anomalies. To
model fetal outcomes in nonhuman primates, we administered Asian-lineage ZIKV …
model fetal outcomes in nonhuman primates, we administered Asian-lineage ZIKV …
[HTML][HTML] The wMel Strain of Wolbachia Reduces Transmission of Chikungunya Virus in Aedes aegypti
…, I Dario Velez, BM Christensen, JE Osorio - PLoS neglected …, 2016 - journals.plos.org
Background New approaches to preventing chikungunya virus (CHIKV) are needed
because current methods are limited to controlling mosquito populations, and they have not …
because current methods are limited to controlling mosquito populations, and they have not …
Safety and immunogenicity of a recombinant live attenuated tetravalent dengue vaccine (DENVax) in flavivirus-naive healthy adults in Colombia: a randomised …
Background Dengue virus is the most serious mosquito-borne viral threat to public health and
no vaccines or antiviral therapies are approved for dengue fever. The tetravalent DENVax …
no vaccines or antiviral therapies are approved for dengue fever. The tetravalent DENVax …