Advanced age-related macular degeneration (AMD) is the leading cause of blindness in the
elderly, with limited therapeutic options. Here we report on a study of >12 million variants, …

A glaucoma locus, GLC1A, was identified previously on chromosome 1q. A gene within this
locus (encoding the protein myocilin) subsequently was shown to harbor mutations in 2–4% …

Refractive error is the most common eye disorder worldwide and is a prominent cause of
blindness. Myopia affects over 30% of Western populations and up to 80% of Asians. The …

We report a genome-wide association study for open-angle glaucoma (OAG) blindness
using a discovery cohort of 590 individuals with severe visual field loss (cases) and 3,956 …

Primary open-angle glaucoma (POAG), is a heritable common cause of blindness world-wide.
To identify risk loci, we conduct a large multi-ethnic meta-analysis of genome-wide …

We conducted a genome-wide association study for primary open-angle glaucoma (POAG)
in 1,263 affected individuals (cases) and 34,877 controls from Iceland. We identified a …

Central corneal thickness (CCT) is associated with eye conditions including keratoconus and
glaucoma. We performed a meta-analysis on >20,000 individuals in European and Asian …

Familial exudative vitreoretinopathy (FEVR) is an inherited blinding disorder of the retinal
vascular system. Autosomal dominant FEVR is genetically heterogeneous, but its principal …

Retinopathy of prematurity (ROP) has been recognised as an important cause of childhood
visual impairment and blindness since the 1940s when improved facilities and treatment …

Refractive errors, including myopia, are the most frequent eye disorders worldwide and an
increasingly common cause of blindness. This genome-wide association meta-analysis in …