Neural circuit mapping is generating datasets of tens of thousands of labeled neurons. New
computational tools are needed to search and organize these data. We present NBLAST, a …

To analyse neuron data at scale, neuroscientists expend substantial effort reading documentation,
installing dependencies and moving between analysis and visualisation environments…

We introduce a cost-effective and easily implementable scan unit that converts any camera-based
microscope with optical sectioning capability into a multi-angle projection imaging …

Macropinocytosis is used by a variety of amoebae for feeding on liquid medium. The amoebae
project cups and ruffles from their plasma membrane, driven by actin polymerization, and …

Polarized cells rely on a polarized cytoskeleton to function. Yet, how cortical polarity cues
induce cytoskeleton polarization remains elusive. Here, we capitalized on recently established …

Herpesviruses are large and complex viruses that have a long history of coevolution with
their host species. One important factor in the virus–host interaction is the alteration of …

Mitochondrial dysfunction has long been implicated in the neurodegenerative disorder
Parkinson's disease (PD); however, it is unclear how mitochondrial impairment and α-synuclein …

… In an attempt to counter these issues, Manton & Rees proposed an LSFM-SIM system
featuring three mutually orthogonal objectives [103]. However, the use of 0.8 NA objectives, …

The germination of Bacillus spores is triggered by certain amino acids and sugar molecules
which permeate the outermost layers of the spore to interact with receptor complexes that …

Wide-field fluorescence microscopy, while much faster than confocal microscopy, suffers
from a lack of optical sectioning and poor axial resolution. 3D structured illumination …