User profiles for J. A. Daros
 | José-Antonio DaròsIBMCP (CSIC-Universitat Politècnica de València) Verified email at ibmcp.upv.es Cited by 6101 |
Viroids and viroid-host interactions
… Emilio Martínez de Alba, 1 José-Antonio Daròs, 1 and Francesco Di Serio 2 … Flores
and JA Daròs laboratories has been supported by the Ministerio de Ciencia y Tecnología (BMC2002-…
and JA Daròs laboratories has been supported by the Ministerio de Ciencia y Tecnología (BMC2002-…
[HTML][HTML] The fittest versus the flattest: experimental confirmation of the quasispecies effect with subviral pathogens
The “survival of the fittest” is the paradigm of Darwinian evolution in which the best-adapted
replicators are favored by natural selection. However, at high mutation rates, the fittest …
replicators are favored by natural selection. However, at high mutation rates, the fittest …
Replication of avocado sunblotch viroid: evidence for a symmetric pathway with two rolling circles and hammerhead ribozyme processing.
JA Daròs, JF Marcos, C Hernandez… - Proceedings of the …, 1994 - National Acad Sciences
The structure of a series of RNAs extracted from avocado infected by the 247-nt avocado
sunblotch viroid (ASBVd) was investigated. The identification of multistranded complexes …
sunblotch viroid (ASBVd) was investigated. The identification of multistranded complexes …
Mechanisms of genetic robustness in RNA viruses
Two key features of RNA viruses are their compacted genomes and their high mutation rate.
Accordingly, deleterious mutations are common and have an enormous impact on viral …
Accordingly, deleterious mutations are common and have an enormous impact on viral …
Viroids: an Ariadne's thread into the RNA labyrinth
Viroids are structurally, functionally and evolutionarily different from viruses. Despite their
small, non‐protein‐encoding, single‐stranded circular RNA genome, viroids can infect higher …
small, non‐protein‐encoding, single‐stranded circular RNA genome, viroids can infect higher …
Efficient Cas9 multiplex editing using unspaced sgRNA arrays engineering in a Potato virus X vector
Systems based on the clustered, regularly interspaced, short palindromic repeat (CRISPR)
and CRISPR‐associated proteins (Cas) have revolutionized genome editing in many …
and CRISPR‐associated proteins (Cas) have revolutionized genome editing in many …
[HTML][HTML] A chloroplast protein binds a viroid RNA in vivo and facilitates its hammerhead‐mediated self‐cleavage
Viroids, small single‐stranded circular RNAs (246–401 nucleotides), do not have mRNA
capacity and must recruit host proteins to assist in the steps of their biological cycle. The nature …
capacity and must recruit host proteins to assist in the steps of their biological cycle. The nature …
[HTML][HTML] Processing of nuclear viroids in vivo: an interplay between RNA conformations
… Daròs, unpublished data). The adoption in vivo of the double-stranded structure with a GC-rich
central region containing the cleavage sites could be promoted by hairpin I because prior …
central region containing the cleavage sites could be promoted by hairpin I because prior …
[HTML][HTML] Viroid replication: rolling-circles, enzymes and ribozymes
Viroids, due to their small size and lack of protein-coding capacity, must rely essentially on
their hosts for replication. Intriguingly, viroids have evolved the ability to replicate in two …
their hosts for replication. Intriguingly, viroids have evolved the ability to replicate in two …
Viroid RNA redirects host DNA ligase 1 to act as an RNA ligase
Viroids are a unique class of noncoding RNAs: composed of only a circular, single-stranded
molecule of 246–401 nt, they manage to replicate, move, circumvent host defenses, and …
molecule of 246–401 nt, they manage to replicate, move, circumvent host defenses, and …