Genome-wide association study identifies 30 loci associated with bipolar disorder

…, TD Als, A Anjorin, V Antilla, S Awasthi, JA Badner… - Nature …, 2019 - nature.com
Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide
association study (GWAS) including 20,352 cases and 31,358 controls of European descent, …

Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia

JA Badner, ES Gershon - Molecular psychiatry, 2002 - nature.com
Badner and Gershon 3 have presented a technique of meta-analysis for published
genome scans. This technique, called the Multiple Scan Probability (MSP) modifies a meta-analysis …

[PDF][PDF] Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder

…, A Goate, MG McInnis, FJ McMahon, JA Badner… - The American Journal of …, 2003 - cell.com
Genome scans of bipolar disorder (BPD) have not produced consistent evidence for linkage.
The rank-based genome scan meta-analysis (GSMA) method was applied to 18 BPD …

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

…, P Asherson, MH Azevedo, L Backlund, JA Badner… - Nature …, 2013 - cdr.lib.unc.edu
Most psychiatric disorders are moderately to highly heritable. The degree to which genetic
variation is unique to individual disorders or shared across disorders is unclear. To examine …

Recurrent 16p11. 2 microdeletions in autism

…, J Sudi, DF Conrad, C Brune, JA Badner… - Human molecular …, 2008 - academic.oup.com
Autism is a childhood neurodevelopmental disorder with a strong genetic component, yet
the identification of autism susceptibility loci remains elusive. We investigated 180 autism …

A genetic study of Hirschsprung disease.

JA Badner, WK Sieber, KL Garver… - American journal of …, 1990 - ncbi.nlm.nih.gov
… HRSD in association with Waardenburg syndrome can beinherited as an incompletely
penetrant autosomal dominant disorder (Badner and Chakravarti, in press); however, the gene for …

[PDF][PDF] Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes

…, MJ Arranz, S Awasthi, SA Bacanu, JA Badner… - Cell, 2018 - cell.com
Schizophrenia and bipolar disorder are two distinct diagnoses that share symptomology.
Understanding the genetic factors contributing to the shared and disorder-specific symptoms …

[PDF][PDF] Genetic control of individual differences in gene-specific methylation in human brain

D Zhang, L Cheng, JA Badner, C Chen, Q Chen… - The American Journal of …, 2010 - cell.com
We have observed extensive interindividual differences in DNA methylation of 8590 CpG
sites of 6229 genes in 153 human adult cerebellum samples, enriched in CpG island "shores" …

Genome-wide association study of bipolar disorder in European American and African American individuals

EN Smith, CS Bloss, JA Badner, T Barrett… - Molecular …, 2009 - nature.com
To identify bipolar disorder (BD) genetic susceptibility factors, we conducted two genome-wide
association (GWA) studies: one involving a sample of individuals of European ancestry (…

Novel submicroscopic chromosomal abnormalities detected in autism spectrum disorder

…, RA Kumar, S Liu, S Karamohamed, JA Badner… - Biological …, 2008 - Elsevier
Badner reported no biomedical interests or potential conflicts of interest. Seiichi Matsui
reported no biomedical interests or potential conflicts of interest. Jeffrey Conroy reported no …