[PDF][PDF] Hepatitis C, interferon alfa, and depression

D Zdilar, K Franco‐Bronson, N Buchler, JA Locala… - …, 2000 - Wiley Online Library
Hepatitis C virus (HCV) infection is the most common cause of chronic liver disease in the
United States. An estimated 1.8% of the US population carries the antibody to HCV, with 74% …

Germline Chd8 haploinsufficiency alters brain development in mouse

…, MD Schaffler, AA Wade, R Catta-Preta, I Zdilar… - Nature …, 2017 - nature.com
The chromatin remodeling gene CHD8 represents a central node in neurodevelopmental
gene networks implicated in autism. We examined the impact of germline heterozygous …

Bleeding risk assessment using whole blood impedance aggregometry and rotational thromboelastometry in patients following cardiac surgery

…, S Konosic, L Svetina, A Lekić, B Zdilar… - Journal of thrombosis …, 2013 - Springer
Excessive bleeding after cardiopulmonary bypass (CPB) is risk factor for adverse outcomes
after elective cardiac surgery (ECS). Differentiating between patients who bleed due to …

Sequential perturbations to mouse corticogenesis following in utero maternal immune activation

…, S Cameron, K Prendergast, L Su-Feher, I Zdilar… - Elife, 2021 - elifesciences.org
In utero exposure to maternal immune activation (MIA) is an environmental risk factor for
neurodevelopmental and neuropsychiatric disorders. Animal models provide an opportunity to …

[HTML][HTML] Clustering of largely right-censored oropharyngeal head and neck cancer patients for discriminative groupings to improve outcome prediction

J Tosado, L Zdilar, H Elhalawani, B Elgohari… - Scientific reports, 2020 - nature.com
Clustering is the task of identifying groups of similar subjects according to certain criteria.
The AJCC staging system can be thought as a clustering mechanism that groups patients …

Parallel functional testing identifies enhancers active in early postnatal mouse brain

…, L Su-Feher, K Cichewicz, TL Warren, I Zdilar… - elife, 2021 - elifesciences.org
Enhancers are cis-regulatory elements that play critical regulatory roles in modulating
developmental transcription programs and driving cell-type-specific and context-dependent gene …

Single cell enhancer activity distinguishes GABAergic and cholinergic lineages in embryonic mouse basal ganglia

…, KJ Lim, AR Ypsilanti, I Zdilar… - Proceedings of the …, 2022 - National Acad Sciences
Enhancers integrate transcription factor signaling pathways that drive cell fate specification
in the developing brain. We paired enhancer labeling and single-cell RNA-sequencing (…

[HTML][HTML] Deletion of a non-canonical regulatory sequence causes loss of Scn1a expression and epileptic phenotypes in mice

…, AA Wade, R Catta-Preta, L Su-Feher, I Zdilar… - Genome medicine, 2021 - Springer
Background Genes with multiple co-active promoters appear common in brain, yet little is
known about functional requirements for these potentially redundant genomic regulatory …

Evaluating the effect of right-censored end point transformation for radiomic feature selection of data from patients with oropharyngeal cancer

L Zdilar, DM Vock, GE Marai, CD Fuller… - JCO clinical cancer …, 2018 - ascopubs.org
Purpose To evaluate the effect of transforming a right-censored outcome into binary, continuous,
and censored-aware representations on radiomics feature selection and subsequent …

Novel receptor protein tyrosine phosphatase (RPTPρ) and acidic fibroblast growth factor (FGF‐1) transcripts delineate a rostrocaudal boundary in the granule cell …

…, A Frostholm, JE Evans, D Zdilar… - Journal of …, 1998 - Wiley Online Library
We have identified a novel receptor‐like protein tyrosine phosphatase (RPTPρ) transcript
whose expression in the cerebellar cortex is restricted to the granule cell layer of lobules 1–6. …