User profiles for I. Shabalina

Irina Shabalina

Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University
Verified email at wgi.su.se
Cited by 6415

Origins and evolution of eukaryotic RNA interference

SA Shabalina, EV Koonin - Trends in ecology & evolution, 2008 - cell.com
Small interfering RNAs (siRNAs) and genome-encoded microRNAs (miRNAs) silence genes
via complementary interactions with mRNAs. With thousands of miRNA genes identified …

Sounds of silence: synonymous nucleotides as a key to biological regulation and complexity

SA Shabalina, NA Spiridonov… - Nucleic acids research, 2013 - academic.oup.com
Messenger RNA is a key component of an intricate regulatory network of its own. It
accommodates numerous nucleotide signals that overlap protein coding sequences and are …

Genetic architecture of human pain perception

…, AG Nackley, IE Tchivileva, SA Shabalina… - TRENDS in …, 2007 - cell.com
Pain is emotionally detrimental and consciously avoided; however, it is absolutely crucial for
our survival. Pain perception is one of the most complicated measurable traits because it is …

Genetic basis for individual variations in pain perception and the development of a chronic pain condition

…, I Belfer, D Goldman, K Xu, SA Shabalina… - Human molecular …, 2005 - academic.oup.com
Pain sensitivity varies substantially among humans. A significant part of the human population
develops chronic pain conditions that are characterized by heightened pain sensitivity. …

[BOOK][B] arXiv: Handbook of LHC Higgs Cross Sections: 4. Deciphering the Nature of the Higgs Sector

…, R Santos, MV Garzelli, S Sekula, E Shabalina… - 2016 - cds.cern.ch
This Report summarizes the results of the activities of the LHC Higgs Cross Section Working
Group in the period 2014–2016. The main goal of the working group was to present the state…

[HTML][HTML] A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with …

KS Makarova, NV Grishin, SA Shabalina, YI Wolf… - Biology direct, 2006 - Springer
Background All archaeal and many bacterial genomes contain Clustered Regularly Interspaced
Short Palindrome Repeats (CRISPR) and variable arrays of the CRISPR-associated (cas…

Human Catechol-O-Methyltransferase Haplotypes Modulate Protein Expression by Altering mRNA Secondary Structure

AG Nackley, SA Shabalina, IE Tchivileva, K Satterfield… - Science, 2006 - science.org
Catechol-O-methyltransferase (COMT) is a key regulator of pain perception, cognitive function,
and affective mood. Three common haplotypes of the human COMT gene, divergent in …

[HTML][HTML] Chronic peroxisome proliferator-activated receptor γ (PPARγ) activation of epididymally derived white adipocyte cultures reveals a population of …

N Petrovic, TB Walden, IG Shabalina… - Journal of Biological …, 2010 - ASBMB
The recent insight that brown adipocytes and muscle cells share a common origin and in this
respect are distinct from white adipocytes has spurred questions concerning the origin and …

[PDF][PDF] UCP1 in brite/beige adipose tissue mitochondria is functionally thermogenic

IG Shabalina, N Petrovic, JMA de Jong, AV Kalinovich… - Cell reports, 2013 - cell.com
The phenomenon of white fat "browning," in which certain white adipose tissue depots
significantly increase gene expression for the uncoupling protein UCP1 and thus supposedly …

Inclusive particle production in 400 GeV/c pp-interactions

…, JM Salicio, S Saran, M Sessa, EK Shabalina… - Zeitschrift für Physik C …, 1991 - Springer
We report on a study of inclusive particle production in pp-interactions at 400 GeV/c. The
data are based on 472 K reconstructed events recorded in the NA 27 experiment using the …