User profiles for I. Heemskerk
Idse HeemskerkUniversity of Michigan Verified email at umich.edu Cited by 2585 |
New fundamentals in hemostasis
HH Versteeg, JWM Heemskerk, M Levi… - Physiological …, 2013 - journals.physiology.org
Hemostasis encompasses the tightly regulated processes of blood clotting, platelet
activation, and vascular repair. After wounding, the hemostatic system engages a plethora of …
activation, and vascular repair. After wounding, the hemostatic system engages a plethora of …
Platelet activation and blood coagulation
JWM Heemskerk, EM Bevers… - Thrombosis and …, 2002 - thieme-connect.com
Platelet activation and blood coagulation are complementary, mutually dependent processes
in haemostasis and thrombosis. Platelets interact with several coagulation factors, while …
in haemostasis and thrombosis. Platelets interact with several coagulation factors, while …
Platelet biology and functions: new concepts and clinical perspectives
PEJ van der Meijden, JWM Heemskerk - Nature Reviews Cardiology, 2019 - nature.com
Platelets—blood cells continuously produced from megakaryocytes mainly in the bone
marrow—are implicated not only in haemostasis and arterial thrombosis, but also in other …
marrow—are implicated not only in haemostasis and arterial thrombosis, but also in other …
Tumor antigen–specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired
…, LA Johnson, B Heemskerk… - Blood, The Journal …, 2009 - ashpublications.org
Tumor antigen–specific T cells are found within melanomas, yet tumors continue to grow.
Although the tumor microenvironment is thought to influence the suppression of tumor-reactive …
Although the tumor microenvironment is thought to influence the suppression of tumor-reactive …
Bilateral deep brain stimulation vs best medical therapy for patients with advanced Parkinson disease: a randomized controlled trial
…, A Samii, S Horn, J Bronstein, G Stoner, J Heemskerk… - Jama, 2009 - jamanetwork.com
Context Deep brain stimulation is an accepted treatment for advanced Parkinson disease (PD),
although there are few randomized trials comparing treatments, and most studies …
although there are few randomized trials comparing treatments, and most studies …
Holography from conformal field theory
I Heemskerk, J Penedones… - Journal of High Energy …, 2009 - iopscience.iop.org
The locality of bulk physics at distances below the AdS length scale is one of the remarkable
aspects of AdS/CFT duality, and one of the least tested. It requires that the AdS radius be …
aspects of AdS/CFT duality, and one of the least tested. It requires that the AdS radius be …
Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma
…, D Philips, A Velds, M Toebes, B Heemskerk… - Journal of Clinical …, 2013 - ascopubs.org
… P Kvistborg, CJ Shu, B Heemskerk, etal: TIL therapy broadens the tumor-reactive CD8(+)
T cell compartment in melanoma patients Oncoimmunology 1: 409– 418,2012 … Bianca …
T cell compartment in melanoma patients Oncoimmunology 1: 409– 418,2012 … Bianca …
[HTML][HTML] The challenge of mapping the human connectome based on diffusion tractography
Tractography based on non-invasive diffusion imaging is central to the study of human brain
connectivity. To date, the approach has not been systematically validated in ground truth …
connectivity. To date, the approach has not been systematically validated in ground truth …
Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord
The differentiation of distinct cell types in the ventral neural tube depends on local inductive
signals from the notochord. We have isolated a vertebrate homolog of the Drosophila …
signals from the notochord. We have isolated a vertebrate homolog of the Drosophila …
[HTML][HTML] Glycoprotein VI but not α2β1 integrin is essential for platelet interaction with collagen
…, R Mokhtari-Nejad, T Lindhout, JWM Heemskerk… - The EMBO …, 2001 - embopress.org
Platelet adhesion on and activation by components of the extracellular matrix are crucial to
arrest post-traumatic bleeding, but can also harm tissue by occluding diseased vessels. …
arrest post-traumatic bleeding, but can also harm tissue by occluding diseased vessels. …