User profiles for I. Germanguz

Igal Germanguz

UCLA
Verified email at ucla.edu
Cited by 772

Multipotent vasculogenic pericytes from human pluripotent stem cells promote recovery of murine ischemic limb

…, M Tzukerman, N Zeevi-Levin, A Novak, I Germanguz… - Circulation, 2012 - Am Heart Assoc
Background— Pericytes represent a unique subtype of microvessel-residing perivascular
cells with diverse angiogenic functions and multilineage developmental features of …

Molecular characterization and functional properties of cardiomyocytes derived from human inducible pluripotent stem cells

I Germanguz, O Sedan, N Zeevi‐Levin… - Journal of cellular …, 2011 - Wiley Online Library
In view of the therapeutic potential of cardiomyocytes derived from induced pluripotent stem
(iPS) cells (iPS‐derived cardiomyocytes), in the present study we investigated in iPS‐…

Induced pluripotent stem cells (iPSCs) derived from different cell sources and their potential for regenerative and personalized medicine

R Shtrichman, I Germanguz… - Current molecular …, 2013 - ingentaconnect.com
Human induced pluripotent stem cells (hiPSCs) have great potential as a robust source of
progenitors for regenerative medicine. The novel technology also enables the derivation of …

[HTML][HTML] Altered A-to-I RNA editing in human embryogenesis

R Shtrichman, I Germanguz, R Mandel, A Ziskind… - 2012 - journals.plos.org
Post-transcriptional events play an important role in human development. The question
arises as to whether Adenosine to Inosine RNA editing, catalyzed by the ADAR (Adenosine …

[PDF][PDF] Loss of MECP2 leads to activation of P53 and neuronal senescence

…, J Cinkornpumin, C Salas, JC Park, I Germanguz… - Stem Cell Reports, 2018 - cell.com
To determine the role for mutations of MECP2 in Rett syndrome, we generated isogenic lines
of human induced pluripotent stem cells, neural progenitor cells, and neurons from patient …

Enhanced reprogramming and cardiac differentiation of human keratinocytes derived from plucked hair follicles, using a single excisable lentivirus

A Novak, R Shtrichman, I Germanguz… - … " Cloning and Stem …, 2010 - liebertpub.com
Induced pluripotent stem cells (iPSCs) represent an ideal cell source for future cell therapy
and regenerative medicine. However, most iPSC lines described to date have been isolated …

Four twist genes in zebrafish, four expression patterns

I Germanguz, D Lev, T Waisman… - … Dynamics: An Official …, 2007 - Wiley Online Library
Twist genes code for regulatory bHLH proteins essential for embryonic development and
conserved across the metazoa. There are four genes that constitute the zebrafish twist family: …

ADAR1 is involved in the regulation of reprogramming human fibroblasts to induced pluripotent stem cells

I Germanguz, R Shtrichman, S Osenberg… - Stem cells and …, 2014 - liebertpub.com
Adenosine-to-inosine (A-to-I) RNA editing is a post-transcriptional, site-specific modification
process that is catalyzed by Adenosine Deaminase Acting on RNA (ADAR) gene family …

Fibrotic human lung extracellular matrix as a disease-specific substrate for 3D in-vitro models of pulmonary fibrosis

I Germanguz, E Aranda, JC Xiong, N Kissel, A Nichols… - bioRxiv, 2019 - biorxiv.org
Idiopathic pulmonary fibrosis (IPF) is an irreversible and uniformly fatal lung disease marked
by destruction and scarring of the lung parenchyma and progressive loss of respiratory …

All four twist genes of zebrafish have partially redundant, but essential, roles in patterning the craniofacial skeleton

I Germanguz, I Gitelman - Journal of Applied Ichthyology, 2012 - Wiley Online Library
Twist proteins are highly conserved transcription factors expressed in the cephalic neural
crest of all vertebrates and may therefore constitute part of the molecular machinery that …