User profiles for I. Berindan-Neagoe

ioana berindan neagoe

University of Medicine and Pharmacy Iuliu Hatieganu Cluj Napoca
Verified email at umfcluj.ro
Cited by 19063

MicroRNAome genome: a treasure for cancer diagnosis and therapy

I BerindanNeagoe, PC Monroig… - CA: a cancer journal …, 2014 - Wiley Online Library
The interplay between abnormalities in genes coding for proteins and noncoding microRNAs
(miRNAs) has been among the most exciting yet unexpected discoveries in oncology over …

[HTML][HTML] A comprehensive review on MAPK: a promising therapeutic target in cancer

…, AG Atanasov, O Slaby, C Ionescu, I Berindan-Neagoe - Cancers, 2019 - mdpi.com
The mitogen-activated protein kinase (MAPK) pathway is an important bridge in the switch
from extracellular signals to intracellular responses. Alterations of signaling cascades are …

The dual role of tumor necrosis factor-alpha (TNF-α) in breast cancer: molecular insights and therapeutic approaches

…, O Baldasici, O Balacescu, I Berindan-Neagoe - Cellular Oncology, 2020 - Springer
Background Breast cancer is the most prevalent cancer among women worldwide and the fifth
cause of death among all cancer patients. Breast cancer development is driven by genetic …

CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer

…, I Tomlinson, M Negrini, I Berindan-Neagoe… - Genome …, 2013 - genome.cshlp.org
The functional roles of SNPs within the 8q24 gene desert in the cancer phenotype are not
yet well understood. Here, we report that CCAT2, a novel long noncoding RNA transcript (…

Junk DNA and the long non-coding RNA twist in cancer genetics

…, K Vincent, M Pichler, R Fodde, I Berindan-Neagoe… - Oncogene, 2015 - nature.com
The central dogma of molecular biology states that the flow of genetic information moves
from DNA to RNA to protein. However, in the last decade this dogma has been challenged by …

[HTML][HTML] Exosomes as divine messengers: are they the Hermes of modern molecular oncology?

…, P Monroig, A Cucuianu, I Berindan-Neagoe… - Cell Death & …, 2015 - nature.com
Exosomes are cell-derived vesicles that convey key elements with the potential to modulate
intercellular communication. They are known to be secreted from all types of cells, and are …

[HTML][HTML] Hypoxia: overview on hypoxia-mediated mechanisms with a focus on the role of HIF genes

…, SM Ciortea, C Crivii, I Berindan-Neagoe - International journal of …, 2019 - mdpi.com
Hypoxia represents a frequent player in a number of malignancies, contributing to the
development of the neoplastic disease. This review will discuss the means by which hypoxia …

Apoptosis in cancer: key molecular signaling pathways and therapy targets

C Burz, I Berindan-Neagoe, O Balacescu… - Acta oncologica, 2009 - Taylor & Francis
Apoptosis is a physiological process vital for embryologic development and the maintenance
of homeostasis in multicellular organisms, but it is also involved in a wide range of …

Phytol: A review of biomedical activities

…, F Nicoletti, D Gulei, I Berindan-Neagoe… - Food and chemical …, 2018 - Elsevier
Phytol (PYT) is a diterpene member of the long-chain unsaturated acyclic alcohols. PYT and
some of its derivatives, including phytanic acid (PA), exert a wide range of biological effects. …

[HTML][HTML] Progresses towards safe and efficient gene therapy vectors

…, C Braicu, LZ Raduly, GA Calin, I Berindan-Neagoe - Oncotarget, 2015 - ncbi.nlm.nih.gov
The emergence of genetic engineering at the beginning of the 1970′ s opened the era of
biomedical technologies, which aims to improve human health using genetic manipulation …