Microtubule cytoskeleton function depends on the dynamic interplay of microtubules and
various microtubule-binding proteins. To gain an understanding of cytoskeleton function at the …

During cell division, microtubules are arranged in a large bipolar structure, the mitotic
spindle, to segregate the duplicated chromosomes. Antiparallel microtubule overlaps in the …

… Surrey acknowledge financial support from the Deutsche Forschungsgemeinschaft, and IA
Telley acknowledges support from the European Union STREP Active Biomics and the Swiss …

Kinesin motor proteins are thought to move exclusively in either one or the other direction
along microtubules. Proteins of the kinesin-5 family are tetrameric microtubule cross-linking …

Inside cells, a multitude of molecular motors and other microtubule-associated proteins are
expected to compete for binding to a limited number of binding sites available on …

The positioning of the nucleus, the central organelle of the cell, is an active and regulated
process crucially linked to cell cycle, differentiation, migration, and polarity. Alterations in …

Cell and tissue functions rely on the genetic programmes and cascades of biochemical signals.
It has become evident during the past decade that the physical properties of soft material …

To study the dynamics of individual half-sarcomeres in striated muscle contraction, myofibrils
prepared from rabbit psoas muscle and left ventricles of guinea pig were immunostained …

Processive motor proteins are stochastic steppers that perform actual mechanical steps for
only a minor fraction of the time they are bound to the filament track. Motors usually work in …

We examined length changes of individual half‐sarcomeres during and after stretch in actively
contracting, single rabbit psoas myofibrils containing 10–30 sarcomeres. The myofibrils …