OBJECTIVE: To review the literature and to identify practice gaps in the management of the
hospitalized Parkinson’s disease (PD) patient. BACKGROUND: Patients with PD are …

Objective: Tourette’s syndrome is polygenic and highly heritable. Genome-wide association
study (GWAS) approaches are useful for interrogating the genetic architecture and …

Importance Collective evidence has strongly suggested that deep brain stimulation (DBS) is
a promising therapy for Tourette syndrome. Objective To assess the efficacy and safety of …

OBJECTIVE: To investigate the ability of the Timed Up & Go test to identify patients with
Parkinson's disease at risk for a fall. DESIGN: Cross-sectional cohort study. SETTING: Sixteen …

A combination of motor and phonic tics is the hallmark of Tourette syndrome (TS). This
complex neuropsychiatric disorder is often associated with psychiatric comorbidities such as …

Tourette syndrome (TS) is a model neuropsychiatric disorder thought to arise from abnormal
development and/or maintenance of cortico-striato-thalamo-cortical circuits. TS is highly …

Whole-exome sequencing (WES) and de novo variant detection have proven a powerful
approach to gene discovery in complex neurodevelopmental disorders. We have completed …

Purpose of Review This study aims to examine the treatments currently available for Tourette
syndrome (TS) and to discuss evolving therapies, spanning behavioral, pharmacologic, …

Background and Purpose: Gait dysfunction is a common target for pharmacological,
behavioral, and surgical interventions in persons with Parkinson disease. However, the …

We previously established the contribution of de novo damaging sequence variants to
Tourette disorder (TD) through whole-exome sequencing of 511 trios. Here, we sequence an …