User profiles for H. Youk

Hyun Youk

- Verified email at umassmed.edu - Cited by 1603

hyun youk

- Verified email at yonsei.ac.kr - Cited by 143

Autocrine signaling and quorum sensing: extreme ends of a common spectrum

BA Doğaner, LKQ Yan, H Youk - Trends in cell biology, 2016 - cell.com
‘Secrete-and-sense cells' can communicate by secreting a signaling molecule while also
producing a receptor that detects the molecule. The cell can potentially ‘talk' to itself (‘self-…

Snowdrift game dynamics and facultative cheating in yeast

J Gore, H Youk, A Van Oudenaarden - Nature, 2009 - nature.com
The origin of cooperation is a central challenge to our understanding of evolution 1 , 2 , 3 . The
fact that microbial interactions can be manipulated in ways that animal interactions cannot …

Secreting and sensing the same molecule allows cells to achieve versatile social behaviors

H Youk, WA Lim - Science, 2014 - science.org
… Specifically, T H cells increase both the expression of high-affinity IL-2 receptor and … that
naïve T H cells can realize a tunable hybrid of the two T H cell states, T H 1 and T H 2, which is …

Enhanced anticancer efficacy of α-tocopheryl succinate by conjugation with polyethylene glycol

HJ Youk, E Lee, MK Choi, YJ Lee, JH Chung… - Journal of controlled …, 2005 - Elsevier
… We found that treatment for 24 h with 40 μM TPGS led to … We found that treatment of H460
cells for 24 h with 40 μM TPGS… chromatin condensation, after 24 h, whereas the same dose of …

[HTML][HTML] Modeling cell–cell communication for immune systems across space and time

H Daneshpour, H Youk - Current Opinion in Systems Biology, 2019 - Elsevier
Communicating is crucial for cells to coordinate their behaviors. Immunological processes,
involving diverse cytokines and cell types, are ideal for developing frameworks for modeling …

Growth landscape formed by perception and import of glucose in yeast

H Youk, A Van Oudenaarden - Nature, 2009 - nature.com
… in log-phase for roughly 12 h. This procedure ensured that the … (Hitachi U-1800) (roughly
15 h after dilution), the cells had … zero during a period of roughly 24 h. By looking at the cells …

[HTML][HTML] Evaluation and management of platelet transfusion refractoriness

HJ Youk, SH Hwang, HB Oh, DH Ko - Blood research, 2022 - ncbi.nlm.nih.gov
… However, in one study, when IVIg was administered together with PLT components, the 1
h CCI improved, but the 24 h CCI did not show any difference. Therefore, this method has not …

Yeasts collectively extend the limits of habitable temperatures by secreting glutathione

DS Laman Trip, H Youk - Nature Microbiology, 2020 - nature.com
… For the first 48 h of incubation, we measured the number of colony-forming units by taking
out a small-volume aliquot from the liquid cultures at high temperatures and distributing …

[PDF][PDF] Molecular-level tuning of cellular autonomy controls the collective behaviors of cell populations

T Maire, H Youk - Cell systems, 2015 - cell.com
… Maire and Youk develop a conceptual framework for understanding the unicellular and
multicellular control of gene expression for a ubiquitous class of cells that secretes and senses a …

[HTML][HTML] Macroscopic quorum sensing sustains differentiating embryonic stem cells

…, CH Chao, TG Fazzio, H Youk - Nature chemical …, 2023 - nature.com
h, Model-produced curves for collective growth with a threshold population density (solutions
of Eq. 2 in Methods… i, Fold change in number of cells after time t 1 , read off from curves in h. …