The developmental, molecular, and transport biology of Malpighian tubules

KW Beyenbach, H Skaer… - Annual review of …, 2010 - annualreviews.org
Molecular biology is reaching new depths in our understanding of the development and
physiology of Malpighian tubules. In Diptera, Malpighian tubules derive from ectodermal cells …

Intercellular junctions in insect tissues

NJ Lane, HIB Skaer - Advances in insect physiology, 1980 - Elsevier
Publisher Summary This chapter reviews the development of intercellular junctions in insect
tissues. Studies that have been made on developing junctions show that pleated septate, …

The insect nephrocyte is a podocyte-like cell with a filtration slit diaphragm

…, M Wilsch-Bräuninger, M Ruiz-Gómez, H Skaer… - Nature, 2009 - nature.com
h, i, High magnification of the garland nephrocyte cell surface (h) and nephrocyte
diaphragm (i) showing the nephrocyte diaphragm (arrowhead) and extracellular lacunae (asterisk). …

[HTML][HTML] Bringing together components of the fly renal system

B Denholm, H Skaer - Current opinion in genetics & development, 2009 - Elsevier
… animals by tubular epithelia in which a primary urine, isosmotic with the blood/body fluids
is modified by the activity of transporters to retrieve valuable ions and molecules, to balance H

[PDF][PDF] Hemocyte-secreted type IV collagen enhances BMP signaling to guide renal tubule morphogenesis in Drosophila

…, C Hooley, N Hu, C Scahill, H Weavers, H Skaer - Developmental cell, 2010 - cell.com
… into the BM around the tubules completely fails (Figures S2H and S2I) and the anterior
tubules project to the posterior (Figure 3H). Together these data show that the normal deposition …

The Drosophila genes crumbs and stardust are involved in the biogenesis of adherens junctions

F Grawe, A Wodarz, B Lee, E Knust, H Skaer - Development, 1996 - journals.biologists.com
… at the apical end of the lateral border (H, shown at higher magnification in inset) or occasionally
a weak SAJ can be seen (epidermis, arrowhead in H). Defects in the organisation of the …

Teashirt 3 is necessary for ureteral smooth muscle differentiation downstream of SHH and BMP4

…, DA Long, C Vola, D Jenkins, AN Garratt, H Skaer… - 2008 - journals.biologists.com
… (DH) Immunostaining for TSHZ3 (green) and nuclei (DAPI, blue) at E15.5 in metanephros
(D), ureter (E) and bladder (F) and at E18.5 in ureter (G) and the bladder (H). Broken line in H

[PDF][PDF] Dual origin of the renal tubules in Drosophila: mesodermal cells integrate and polarize to establish secretory function

…, R Artero, P Lawrence, S Maddrell, M Baylies, H Skaer - Current Biology, 2003 - cell.com
… (E–H) Expression of G447.2GAL4 in cells of the caudal mesoderm … Skaer for assistance with
statistical analysis, A. North for help … Skaer, H. (1989). Cell division in the development of the …

Compartmentalisation of Rho regulators directs cell invagination during tissue morphogenesis

…, B Denholm, D Azevedo, S Sotillos, P Martin, H Skaer… - 2006 - journals.biologists.com
During development, small RhoGTPases control the precise cell shape changes and movements
that underlie morphogenesis. Their activity must be tightly regulated in time and space, …

Secretion and movement of wingless protein in the epidermis of the Drosophila embryo

F González, L Swales, A Bejsovec, H Skaer… - Mechanisms of …, 1991 - Elsevier
… ~M, for periods of time between 10 min and 2 h. In all cases, after fixation and staining with
… Intracellular location of the wingless and engrailed products in the ectoderm of embryos 5 h