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[HTML][HTML] Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFκB activation in primary hippocampal neurons

…, YH Che, H Matsuzaki, S Ogawa, H Okado… - Journal of Biological …, 1999 - ASBMB
Emerging data indicate that tumor necrosis factor (TNF) exerts a neuroprotective effect in
response to brain injury. Here we examined the mechanism of TNF in preventing neuronal …

[HTML][HTML] Molecular pathways underlying projection neuron production and migration during cerebral cortical development

C Ohtaka-Maruyama, H Okado - Frontiers in neuroscience, 2015 - frontiersin.org
Glutamatergic neurons of the mammalian cerebral cortex originate from radial glia (RG)
progenitors in the ventricular zone (VZ). During corticogenesis, neuroblasts migrate toward the …

Cloning by functional expression of platelet-activating factor receptor from guinea-pig lung

…, M Minami, T Watanabe, Y Seyama, H Okado, H Toh… - Nature, 1991 - nature.com
… 5 into COKFu cells resulted in decreased expression of myc and p53 genes, and increased
expression of the K-ras-2 gene without significant change in transcription of the H-ras-1 gene…

Continual remodeling of postsynaptic density and its regulation by synaptic activity

S Okabe, HD Kim, A Miwa, T Kuriu, H Okado - Nature neuroscience, 1999 - nature.com
… axon was also confirmed by staining with anti-neurofilament H antibody (data not shown). …
(a, b) Time-lapse images of the same dendritic segment taken before and after a 24-h interval. (…

Blockage of Ca2+-permeable AMPA receptors suppresses migration and induces apoptosis in human glioblastoma cells

…, N Hagimura, H Okado, A Miwa, H Kurihara… - Nature medicine, 2002 - nature.com
… Cells were cultured inside a ring that was removed 48 h after viral infection. The number of
cells that crossed the border of the cloning ring during the next 24 h was counted. The mean …

Glia-Synapse Interaction Through Ca2+-Permeable AMPA Receptors in Bergmann Glia

M Iino, K Goto, W Kakegawa, H Okado, M Sudo… - Science, 2001 - science.org
Glial cells express a variety of neurotransmitter receptors. Notably, Bergmann glial cells in
the cerebellum have Ca 2+ -permeable α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic …

Akt/protein kinase B prevents injury-induced motoneuron death and accelerates axonal regeneration

…, T Obata, A Miwa, H Okado, H Kiyama - Journal of …, 2000 - Soc Neuroscience
… Kikkawa and H. Konishi) and anti-HA monoclonal antibody (12CA5); for da-MEK, anti-c-Myc
monoclonal … IgG(H) indicated by arrows inC and D shows the position of IgG heavy chain. …

Spine formation and correlated assembly of presynaptic and postsynaptic molecules

S Okabe, A Miwa, H Okado - Journal of Neuroscience, 2001 - Soc Neuroscience
Hippocampal pyramidal neurons in culture showed a developmental shift in synapse
distribution from dendritic shafts to spines. Using dual wavelength time-lapse fluorescence …

[PDF][PDF] Glial Nax channels control lactate signaling to neurons for brain [Na+] sensing

…, TY Hiyama, A Nagakura, A Fujikawa, H Okado… - Neuron, 2007 - cell.com
Sodium (Na) homeostasis is crucial for life, and Na levels in body fluids are constantly monitored
in the brain. The subfornical organ (SFO) is the center of the sensing responsible for the …

Ca2+-permeable AMPA receptors regulate growth of human glioblastoma via Akt activation

…, T Watanabe, N Saito, K Tsuzuki, H Okado… - Journal of …, 2007 - Soc Neuroscience
… To examine how glutamate influences tumor growth, we maintained glioblastoma cells in
the control medium for 12 h after plating and then cultured the cells in glutamate- and glutamine…
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