User profiles for H. Kawaji
Hideya KawajiTokyo Metropolitan Institute of Medical Science Verified email at igakuken.or.jp Cited by 28992 |
The systems biology graphical notation
Circuit diagrams and Unified Modeling Language diagrams are just two examples of standard
visual languages that help accelerate work by promoting regularity, removing ambiguity …
visual languages that help accelerate work by promoting regularity, removing ambiguity …
An atlas of active enhancers across human cell types and tissues
… A second hit of 22 nM siRNA was given after 48 h. Cells were collected an additional 48
h after the second hit, and protein depletion was verified by western blotting analysis as …
h after the second hit, and protein depletion was verified by western blotting analysis as …
Genome-wide analysis of mammalian promoter architecture and evolution
…, Y Kitazume, H Kawaji, C Kai, M Nakamura, H Konno… - Nature …, 2006 - nature.com
… 0.01, Kruskal-Willis test) for which we currently have sufficient tags to make assessments (H.
Kawaji et al., data not shown). CpG island promoter regions are also commonly associated …
Kawaji et al., data not shown). CpG island promoter regions are also commonly associated …
Enhanced identification of transcriptional enhancers provides mechanistic insights into diseases
Enhancers are distal cis-regulatory DNA elements that increase the expression of target
genes. Various experimental and computational approaches including chromatin signature …
genes. Various experimental and computational approaches including chromatin signature …
An atlas of human long non-coding RNAs with accurate 5′ ends
Long non-coding RNAs (lncRNAs) are largely heterogeneous and functionally uncharacterized.
Here, using FANTOM5 cap analysis of gene expression (CAGE) data, we integrate …
Here, using FANTOM5 cap analysis of gene expression (CAGE) data, we integrate …
[HTML][HTML] Gateways to the FANTOM5 promoter level mammalian expression atlas
The FANTOM5 project investigates transcription initiation activities in more than 1,000 human
and mouse primary cells, cell lines and tissues using CAGE. Based on manual curation of …
and mouse primary cells, cell lines and tissues using CAGE. Based on manual curation of …
The BioMart community portal: an innovative alternative to large, centralized data repositories
The BioMart Community Portal ( www.biomart.org ) is a community-driven effort to provide a
unified interface to biomedical databases that are distributed worldwide. The portal provides …
unified interface to biomedical databases that are distributed worldwide. The portal provides …
[HTML][HTML] An atlas of combinatorial transcriptional regulation in mouse and man
Combinatorial interactions among transcription factors are critical to directing tissue-specific
gene expression. To build a global atlas of these combinations, we have screened for …
gene expression. To build a global atlas of these combinations, we have screened for …
Cap analysis gene expression for high-throughput analysis of transcriptional starting point and identification of promoter usage
…, K Waki, T Kasukawa, H Kawaji… - Proceedings of the …, 2003 - National Acad Sciences
… in 100 μl, and incubated at 37C for 1 h. After Proteinase K treatment, samples were phenol/…
16C for 16 h. Heating the reaction mixture at 65C for 5 min terminated the ligation reaction. …
16C for 16 h. Heating the reaction mixture at 65C for 5 min terminated the ligation reaction. …
Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells
Although it is generally accepted that cellular differentiation requires changes to transcriptional
networks, dynamic regulation of promoters and enhancers at specific sets of genes has …
networks, dynamic regulation of promoters and enhancers at specific sets of genes has …