User profiles for H. Bien
Heidrun BienQueen Mary University of London Verified email at qmul.ac.uk Cited by 285 |
[HTML][HTML] Macroscopic optical mapping of excitation in cardiac cell networks with ultra-high spatiotemporal resolution
E Entcheva, H Bien - Progress in biophysics and molecular biology, 2006 - Elsevier
… Author links open overlay panel Emilia Entcheva a b , Harold Bien a … cells (Bien et al.,
2003; Entcheva et al., 2004a) and Generation III intensified pco1200 CMOS camera at 200 fps. …
2003; Entcheva et al., 2004a) and Generation III intensified pco1200 CMOS camera at 200 fps. …
Electrospun fine-textured scaffolds for heart tissue constructs
X Zong, H Bien, CY Chung, L Yin, D Fang, BS Hsiao… - Biomaterials, 2005 - Elsevier
The structural and functional effects of fine-textured matrices with sub-micron features on
the growth of cardiac myocytes were examined. Electrospinning was used to fabricate …
the growth of cardiac myocytes were examined. Electrospinning was used to fabricate …
Conversion of tumor-specific CD4+ T-cell tolerance to T-cell priming through in vivo ligation of CD40
EM Sotomayor, I Borrello, E Tubb, FM Rattis, H Bien… - Nature medicine, 1999 - nature.com
Tumor antigen-specific T-cell tolerance limits the efficacy of therapeutic cancer vaccines.
Antigen-presenting cells mediate the induction of T-cell tolerance to self-antigens. We therefore …
Antigen-presenting cells mediate the induction of T-cell tolerance to self-antigens. We therefore …
Reducing excess mortality due to chronic disease in people with severe mental illness: meta-review of health interventions
… (h)Was the scientific quality of the included studies used appropriately in formulating … 5
Brown S, Kim M, Mitchell C, Inskip H. Twenty-five year mortality of a community cohort with …
Brown S, Kim M, Mitchell C, Inskip H. Twenty-five year mortality of a community cohort with …
Functional cardiac cell constructs on cellulose-based scaffolding
E Entcheva, H Bien, L Yin, CY Chung, M Farrell… - Biomaterials, 2004 - Elsevier
… PDMS membranes were prepared in the usual ratio of 1:10 of curing agent to elastomer
and baked for 2 h at 60C. All scaffolds were sterilized in ethanol or using UV light. …
and baked for 2 h at 60C. All scaffolds were sterilized in ethanol or using UV light. …
Stimulating cardiac muscle by light: cardiac optogenetics by cell delivery
Z Jia, V Valiunas, Z Lu, H Bien, H Liu… - Circulation …, 2011 - Am Heart Assoc
Background— After the recent cloning of light-sensitive ion channels and their expression in
mammalian cells, a new field, optogenetics, emerged in neuroscience, allowing for precise …
mammalian cells, a new field, optogenetics, emerged in neuroscience, allowing for precise …
Challenges in Ras therapeutics in pancreatic cancer
M Choi, H Bien, A Mofunanya, S Powers - Seminars in cancer biology, 2019 - Elsevier
… 100 mg orally per day plus MK-2206 135 mg orally once per week or mFOLFOX (oxaliplatin,
85 mg/m 2 intravenous, and fluorouracil, 2400 mg/m 2 intravenous infusion over 46–48 h) …
85 mg/m 2 intravenous, and fluorouracil, 2400 mg/m 2 intravenous infusion over 46–48 h) …
[HTML][HTML] OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology
…, CM Ambrosi, J Yu, JC Williams, H Bien… - Nature …, 2016 - nature.com
… 4) without much effect on CT morphology (h). We demonstrate a fully automated HT version
of OptoDyCE in 96-well format (b) using a custom-built optical setup and an automation …
of OptoDyCE in 96-well format (b) using a custom-built optical setup and an automation …
PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice
…, KK Takeuchi, CJ Halbrook, LV Peverley, H Bien… - Gastroenterology, 2014 - Elsevier
Background & Aims New drug targets are urgently needed for the treatment of patients with
pancreatic ductal adenocarcinoma (PDA). Nearly all PDAs contain oncogenic mutations in …
pancreatic ductal adenocarcinoma (PDA). Nearly all PDAs contain oncogenic mutations in …
[HTML][HTML] Nonmonotone invasion landscape by noise-aware control of metastasis activator levels
… b, Representative images of invading cells at the bottom of the inserts after 16 h–24 h invasion
assays. Cell number was determined using nuclear staining and GFP fluorescence. Scale …
assays. Cell number was determined using nuclear staining and GFP fluorescence. Scale …